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Diagnosis of Pulmonary Embolism with d-Dimer Adjusted to Clinical Probability

Diagnosis of Pulmonary Embolism with d-Dimer Adjusted to Clinical Probability

by Hans Rosenberg | Feb 10, 2020 | Journal Club, landmark, Thrombosis

Methodology Score: 4/5 Usefulness Score: 4.5/5 Kearon C, et al. N Engl J Med. 2019 Nov 28;381(22):2125-2134 Question and Methods: the authors sought to demonstrate safety using a d-dimer cut-off of 1000ng/mL for low pre-test probability patients & a cut-off of...
Pregnancy-Adapted YEARS Algorithm for Diagnosis of Suspected Pulmonary Embolism

Pregnancy-Adapted YEARS Algorithm for Diagnosis of Suspected Pulmonary Embolism

by Hans Rosenberg | Aug 19, 2019 | Journal Club, OBGYN, Thrombosis

Journal Club Summary Methodology Score: 4.5/5 Usefulness Score: 4.5 /5 van der Pol LM, et al. N Engl J Med. 2019 Mar 21;380(12):1139-1149 Question and Methods: Using a prospective cohort study of 510 pregnant women, the authors were trying to see whether an algorithm...
Fibrinolysis in Acute Pulmonary Embolism

Fibrinolysis in Acute Pulmonary Embolism

by Mike Hickey, Peter Reardon | Sep 11, 2018 | Critical Care, Featured

Systemic fibrinolysis (SF) in acute pulmonary embolism (PE) remains a hot topic in acute care medicine. This post will examine the available literature regarding the use of SF in different subtypes of PE. Before examining the literature, we first must review the...

Simplified diagnostic management of suspected pulmonary embolism (the YEARS study): a prospective, multicentre, cohort study

by Hans Rosenberg | Oct 23, 2017 | Journal Club, landmark, Thrombosis

Journal Club Summary Reference: Van der Hulle T, et al. Lancet. 2017 Jul 15;390(10091):289-297.  Methodology Score: 4/5                   Usefulness Score: 3.5/5 Questions and Methods: This multicenter trial implemented the YEARS simplified algorithm for suspected PE...

Prevalence of Pulmonary Embolism among Patients Hospitalized for Syncope.

by emottawa | Dec 5, 2016 | Journal Club

Journal Club Summary Methodology Score: 3.5/5               Usefulness Score:  2/5 Prandoni P, et al. N Engl J Med. 2016 Oct 20;375(16):1524-1531.   Full Article   This cross-sectional multi-center study of Italian patients admitted after an ED presentation for...
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