by Evelyn Tran, Pascale King | Jul 16, 2020 | Featured, Grand Round Summaries, Neurology
Status epilepticus (SE) is considered one of the most common neurological emergencies with an estimated incidence of 20 cases/100,000 people worldwide. Just the facts The distribution is bimodal, peaking in patients <1 and >60 years old. In children, the cause...
by Hans Rosenberg | Mar 2, 2020 | Journal Club, Neurology, Pediatrics
Methodology Score: 4/5 Usefulness Score: 3.5/5 Kapur J et al. N Engl J Med. 2019 Nov 28;381(22):2103-2113. Question and Methods: A multicenter, randomized, blinded, comparative-effectiveness trial to determine the efficacy and safety of fosphenytoin, valproic acid...
by Hans Rosenberg | Jan 27, 2020 | Full Article, Journal Club, Pediatrics
Methodology: 4/5 Usefulness: 4/5 Lyttle MD, et al. Lancet. 2019 May 25;393(10186):2125-2134. Question and Methods: Eclipse was an open label RCT that evaluated time to seizure cessation in pediatric SE between Keppra and Dilantin Findings: They found that Keppra was...
by emottawa | Oct 20, 2014 | Journal Club
Journal Club Summary Methodology Score: 3/5 Usefulness Score: 2.5/5 Chamberlain JM, et al; Pediatric Emergency Care Applied Research Network (PECARN). JAMA.2014 Apr 23-30;311(16):1652-60. doi: 10.1001/jama.2014.2625. Full Article This double-blind, multi-center,...