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Signal or Noise? Using Inflammatory Markers Wisely Through a Bayesian Lens

Signal or Noise? Using Inflammatory Markers Wisely Through a Bayesian Lens

by Lucy Karp | Mar 19, 2026 | Featured, Gastroenterology, Grand Round Summaries, Immunology, Infectious Disease, Most Viewed, Ophthalmology, Rheumatology

There seems to be a growing cultural obsession with “inflammation”. Scroll through social media long enough and you’ll find sweeping claims: inflammation is the root of fatigue, weight gain, menstrual cramps, brain fog, and even depression. And alongside this...
Measles… its backkkk (again)

Measles… its backkkk (again)

by Kevin Guo | Sep 19, 2024 | Dermatology, Featured, Immunology, Infectious Disease, Pediatrics

In the past year, there’s been a growing concern about the rising number of measles cases globally, including in Canada. This resurgence of measles cases in major centers has sparked worry. But is it something we should truly be alarmed about? How concerned...
Development and Validation of a Penicillin Allergy Clinical Decision Rule

Development and Validation of a Penicillin Allergy Clinical Decision Rule

by Hans Rosenberg | Jun 7, 2021 | Featured, Immunology, Infectious Disease, Journal Club

Methodology: 3/5 Usefulness: 2/5 Trubiano JA, et al. JAMA Intern Med. 2020 May 1;180(5):745-752.  Question and Methods: Prospective derivation and subsequent retrospective validation of a clinical decision rule for the detection of patients at low risk for true...
An Update for the Adrenaline Junky: Refine Your Anaphylaxis Management

An Update for the Adrenaline Junky: Refine Your Anaphylaxis Management

by Graham Wilson, Alex Coutin | Mar 18, 2021 | Critical Care, Featured, Grand Round Summaries, Immunology, Main page, Pediatrics

What chief complaint will you manage on both an adult and pediatric emergency shift? When you’re running through differentials for hypotension or shock, what life threatening conditions are on the list? When you think of airways that keep you up at night, scenarios...
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