by Sam Wilson, Venkatesh Thiruganasambandamoorthy | Jun 1, 2026 | Critical Care, Journal Club, Resuscitation
Personalized Hemodynamic Resuscitation Targeting Capillary Refill Time in Early Septic Shock: The ANDROMEDA-SHOCK-2 Randomized Clinical Trial. Hernandez G, ANDROMEDA-SHOCK-2 Investigators for the ANDROMEDA Research Network JAMA. 2025 Oct 29:e2520402. doi:...
by Grace Northrop | May 28, 2026 | Featured
Acute Liver Failure (ALF) is rare, with an estimated incidence of 1–6 cases per million per year in Western countries¹². Despite its rarity, it carries significant morbidity and mortality¹. ALF most often affects previously healthy adults in their 30s; in North...
by Meehan Andrew, Venkatesh Thiruganasambandamoorthy | May 25, 2026 | Journal Club, Neurology
Tenecteplase versus standard medical treatment for basilar artery occlusion within 24 h (TRACE-5): a multicentre, prospective, randomised, open-label, blinded-endpoint, superiority, phase 3 trial Xiong Y, Et al. Lancet. 2026 Feb 21;407(10530):763-772. doi:...
by Lucy Karp, Christian Vaillancourt | Apr 27, 2026 | Critical Care, Featured, Journal Club
A Crossover Trial of Hospital-Wide Lactated Ringer’s Solution versus Normal Saline McIntyre L, et al. Canadian Critical Care Trials Group. A Crossover Trial of Hospital-Wide Lactated Ringer’s Solution versus Normal Saline. N Engl J Med. 2025 Aug...
by Camille Dagenais | Apr 23, 2026 | Critical Care, Featured, Grand Round Summaries, Neurology, Neurosurgery, Resuscitation, Trauma
Traumatic brain injury (TBI) is a common yet challenging presentation in emergency medicine. As CT imaging becomes increasingly sensitive, clinicians are identifying more subtle intracranial injuries. The Brain Injury Guidelines (BIG) and Modified Brain Injury...
