oxygen Archives

Early Restrictive vs Liberal Oxygen for Trauma Patients: The TRAUMOX2 Randomized Clinical Trial

by Kevin Guo, Hans Rosenberg, Krishan Yadav | Mar 31, 2025 | Journal Club, Trauma

Methodology: 4/5 Usefulness: 2/5 Arleth T, et al. JAMA. 2025;333(6):479–489. doi:10.1001/jama.2024.25786 Question and Methods: This multicentered randomized control trial allocated trauma patients to a liberal or restrictive oxygen strategy for 8 hours to examine...

Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure

by Hans Rosenberg | Oct 11, 2021 | Critical Care, Journal Club, Respirology

Methodology: 4/5 Usefulness: 3/5 Schjørring OL, et al. N Engl J Med. 2021 Apr 8;384(14):1301-1311. doi: 10.1056/NEJMoa2032510. Question and Methods: Can a lower PaO2 target (i.e., 60mmHg) compared to higher PaO2 target (i.e., 90mmHg) decrease all cause 90...

Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis

by Hans Rosenberg | Jul 2, 2018 | Journal Club

Journal Club Summary Methodology: 4/5 Usefulness: 4/5 Chu DK, et al. Lancet. 2018 Apr 28;391(10131):1693-1705. Question & Methods: The authors wanted to summarize the best available evidence of RCTs to guide rational use of O2 therapy. Findings: Their review of...

Oxygen Therapy in Suspected Acute Myocardial Infarction

by Hans Rosenberg | Jan 15, 2018 | Cardiology, Journal Club, landmark

Journal Club Summary Hofmann R, et al. N Engl J Med. 2017 Sep 28;377(13):1240-1249. Methodology Score: 4/5 Usefulness Score: 4/5 Question and Methods: This large, registry-based RCT evaluated the effect of oxygen on patient-centered clinical outcomes...

Air Versus Oxygen in ST-Segment–Elevation Myocardial Infarction

by emottawa | Feb 1, 2016 | Journal Club

Journal Club Summary Methodology Score: 3.5/5 Usefulness Score: 3.5/5 Stub D, Smith K, Bernard S, et al. Circulation. 2015 Jun 16;131(24):2143-50. Abstract Link Editorial: Oxygen for ST-Segment–Elevation Myocardial Infarction: Still Up in the Air...