by Hans Rosenberg | Oct 4, 2021 | Featured, Journal Club, Neurology
Methodology: 4/5 Usefulness: 4/5 Perry JJ, et al. BMJ. 2021 Feb 4;372:n49. doi: 10.1136/bmj.n49. Question and methods: This multicenter prospective cohort study validates the Canadian TIA Score and compares it to the ABCD2 and ABCD2i score to identify risk...
by Doran Drew, Josee Malette | May 27, 2021 | Featured, Grand Round Summaries, Neurology, Thrombosis
Addressing the Controversies Around Thrombolytic Therapy (tPA) In our previous blog post, we reviewed the formative literature supporting the currently used tPA time window. The figure below highlights a summary of the time windows investigated within each study and...
by Hans Rosenberg | Nov 9, 2020 | Journal Club, Neurology
Methodology: 2/5 Usefulness: 2/5 Johnston SC, et al. N Engl J Med. 2020 Jul 16;383(3):207-217. Question and Methods: Multicentre, double-blind RCT of ASA vs Ticagrelor-ASA among 11016 patients with high-risk TIA or minor stroke for prevention of stroke/death within 30...
by Michael Hale, Richard Hoang, Shankar Sethuraman | Jun 13, 2019 | Grand Round Summaries, Neurology
Ischemic stroke is one of Canada’s leading causes of morbidity and mortality. Over the last 30 years, we have observed rapid advances concerning how we identify, respond to, and treat patients with acute ischemic stroke. Because this topic is so vast, the focus of...
by emottawa | Oct 11, 2016 | Journal Club
Journal Club Summary Methodology Score: 5/5 Usefulness Score: 3.5/5 Johnston SC, et al. N Engl J Med. 2016 Jul 7;375(1):35-43. Full Article This large international double-blind double-dummy RCT across 33 countries and including 13,199 patients...
