by Doran Drew, Amanda Mattice | Jun 23, 2022 | Critical Care, Featured, Grand Round Summaries, Infectious Disease, Resuscitation
A review of some of the most relevant elements of the 2021 surviving sepsis campaign for the emergency physician. Definitions Our operative definition of sepsis & septic shock are the sepsis-3 definitions [1]. Sepsis: “Sepsis is a life threatening organ...
by Doran Drew | Jun 8, 2021 | Commentary, Critical Care, Grand Round Summaries, Journal Club, Resuscitation
Hey everyone! Buckle up. This is a long one. To provide context, I recently presented a 2-part blog post regarding thrombolytics in acute ischemic stroke. In these posts I explored the foundational literature for this tPA, as well as some of the common controversies I...
by Doran Drew, Josee Malette | May 27, 2021 | Featured, Grand Round Summaries, Neurology, Thrombosis
Addressing the Controversies Around Thrombolytic Therapy (tPA) In our previous blog post, we reviewed the formative literature supporting the currently used tPA time window. The figure below highlights a summary of the time windows investigated within each study and...
by Doran Drew, Josee Malette, Kate O'Connell | May 20, 2021 | Featured, Grand Round Summaries, Neurology, Thrombosis
Review of the formative literature of our current tPA time window in Acute Ischemic Stroke After numerous case series and smaller prospective studies suggesting benefit for thrombolytic therapy (tPA), the early 90s ushered in the era of thrombolytic RCTs for acute...
by Pascale King, Doran Drew | Mar 19, 2020 | Featured
What is Bupropion? Bupropion is an anti-depressant commonly prescribed for seasonal affective disorder, as a smoking cessation aid, and off-label in the management of major depressive disorder. You may know it by the trade names Wellbutrin, Zyban or Champix. While...
