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Liar, Liar, Clot on Fire: Is a Negative D-Dimer Always Enough?

Liar, Liar, Clot on Fire: Is a Negative D-Dimer Always Enough?

by Caroline Gregory | Apr 16, 2026 | cardiac arrest, Cardiology, Featured, Grand Round Summaries, Respirology, Resuscitation, Thrombosis

Venous thromboembolism, which includes deep vein thrombosis (DVT) and pulmonary embolism (PE), is one of the most commonly worked-up diagnoses in the emergency department. Approximately half of all DVTs embolize to the lungs, and the annual incidence of PEs is about 1...
Going viral – Emergency Medicine in the age of algorithms

Going viral – Emergency Medicine in the age of algorithms

by Madison Van Dusen | Apr 9, 2026 | Commentary, Grand Round Summaries

“A patient sits in front of you, phone in hand. ‘I think I have hypertrophic cardiomyopathy… I saw it on TikTok.’” Social media is no longer peripheral to healthcare, it is embedded within it. From how patients interpret symptoms to how clinicians learn, connect, and...
Blood Pressure Targets in Trauma Resuscitation: The New Thinking

Blood Pressure Targets in Trauma Resuscitation: The New Thinking

by Mathieu McKinnon | Mar 26, 2026 | Anesthesiology, Critical Care, Featured, Grand Round Summaries, Resuscitation, Trauma

Blood pressure management in trauma is one of the most deceptively complex decisions we make in the emergency department. In the first hour of resuscitation, competing physiologic priorities collide: permissive hypotension may protect clot integrity in hemorrhagic...
Signal or Noise? Using Inflammatory Markers Wisely Through a Bayesian Lens

Signal or Noise? Using Inflammatory Markers Wisely Through a Bayesian Lens

by Lucy Karp | Mar 19, 2026 | Featured, Gastroenterology, Grand Round Summaries, Immunology, Infectious Disease, Most Viewed, Ophthalmology, Rheumatology

There seems to be a growing cultural obsession with “inflammation”. Scroll through social media long enough and you’ll find sweeping claims: inflammation is the root of fatigue, weight gain, menstrual cramps, brain fog, and even depression. And alongside this...
Vernakalant versus procainamide for rapid cardioversion of patients with acute atrial fibrillation (RAFF4): randomised clinical trial

Vernakalant versus procainamide for rapid cardioversion of patients with acute atrial fibrillation (RAFF4): randomised clinical trial

by Anchaleena Mandal, Christian Vaillancourt | Mar 5, 2026 | Featured

Methodology Score: 4.5/5 Usefulness Score: 4/5 Stiell IG, et al. BMJ. 2025 Nov 11;391:e085632. doi: 10.1136/bmj-2025-085632. Question and Methods: This is a multi-center, open-label, patient randomised trial comparing the effectiveness and safety of cardioversion with...
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