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Optimal Head-of-Bed Positioning Before Thrombectomy in Large Vessel Occlusion Stroke: A Randomized Clinical Trial

Optimal Head-of-Bed Positioning Before Thrombectomy in Large Vessel Occlusion Stroke: A Randomized Clinical Trial

by Faran Khalid, Hans Rosenberg, Ian Stiell | Nov 3, 2025 | Full Article, Journal Club, Neurology

Methodology: 3.5/5 Usefulness: 3.5/5 Alexandrov AW, et al. JAMA Neurol. 2025 Sep 1;82(9):905-914. doi: 10.1001/jamaneurol.2025.2253. Question and Methods: Authors aimed to determine if 0° head positioning reduces neurological deterioration and mortality in stroke...
Not-so-Benign Hematology for the ER Physician

Not-so-Benign Hematology for the ER Physician

by Prince Asare-Agbo | Oct 30, 2025 | Critical Care, Featured, Grand Round Summaries, Hematology, Resuscitation

Blood tests (especially complete blood counts and coagulation markers) are some of the most commonly ordered investigations in both the emergency department and the hospital at large. It’s important for us as emergency physicians to have an excellent understanding of...
Primary Care in the ED: Depression

Primary Care in the ED: Depression

by Courtney Price | Oct 23, 2025 | Grand Round Summaries, mental health, Most Viewed, psychiatry

In this second post on Primary Care in the ED we are going to focus on the acute management and treatment of depression. In part one we focused on HTN and COPD – read more here. ED visits for mental health are rising, and many patients use the ED as their first...
Intra-arterial Tenecteplase for Acute Stroke After Successful Endovascular Therapy: The ANGEL-TNK Randomized Clinical Trial

Intra-arterial Tenecteplase for Acute Stroke After Successful Endovascular Therapy: The ANGEL-TNK Randomized Clinical Trial

by Kaitlin Endres, Hans Rosenberg, Ian Stiell | Oct 22, 2025 | Journal Club, Neurology

Methodology: 4.5/5 Usefulness: 4/5 Miao Z, et al. JAMA. 2025 Aug 19;334(7):582-591. doi: 10.1001/jama.2025.10800. Question and Methods: To compare clinical outcomes in patients with acute LVO for those who received intra-arterial tenecteplase after successful...
Primary Care in the ED: HTN and COPD

Primary Care in the ED: HTN and COPD

by Courtney Price | Oct 16, 2025 | Anesthesiology, Cardiology, CME, emergency, Grand Round Summaries, Respirology

It’s no secret that in Canada, family medicine is in crisis. 6.5 million Canadians are without a family doctor,¹ and in a recent Ontario survey, 65% of family physicians reported preparing to leave their profession or reduce hours over the next five years.² This is...
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