by Lucy Karp, Christian Vaillancourt | Apr 27, 2026 | Critical Care, Featured, Journal Club
A Crossover Trial of Hospital-Wide Lactated Ringer’s Solution versus Normal Saline McIntyre L, et al. Canadian Critical Care Trials Group. A Crossover Trial of Hospital-Wide Lactated Ringer’s Solution versus Normal Saline. N Engl J Med. 2025 Aug...
by Zach MacDonald, Hans Rosenberg, Christian Vaillancourt | Dec 26, 2022 | Critical Care, Journal Club
Methodology: 4/5 Usefulness: 3/5 Meyhoff TS, et al. N Engl J Med. 2022 Jun 30;386(26):2459-2470. Question and Methods: International, stratified, parallel group, open-label, randomized clinical trial where ICU patients were randomized to restrictive or standard fluid...
by Bo Zheng, Richard Hoang, Shankar Sethuraman | May 2, 2019 | Grand Round Summaries
IV fluid is a drug Intravenous fluid administration is the second most common medical intervention next to supplemental oxygen.1 Over 200 million liters of normal saline (NS) is used in the United States annually.2 Intravenous fluids, like any other drug, should be...
by EMOttawa | Nov 18, 2013 | Journal Club, landmark
Journal Club Summary Landmark Series Methodology Score: 4/5 Usefulness Score: 4.5/5 Perner A, et al.; 6S Trial Group; Scandinavian Critical Care Trials Group. N Engl J Med. 2012 Jul 12;367(2):124-34 Article Link This multi-centre, double-blind,...
