by Hans Rosenberg | Dec 7, 2020 | Critical Care, Featured, Infectious Disease, Journal Club
Methodology: 3.5/5 Usefulness: 3.5/5 Ann Intern Med. 2019 Oct 15;171(8):547-554. Cheng MP, et al. Question and Methods: Multi-center diagnostic study that investigated the sensitivity of post-antimicrobial blood cultures compared to pre-antimicrobial blood cultures in...
by Garrick Mok, Pascale King | May 7, 2020 | Critical Care, Featured, Grand Round Summaries, Infectious Disease, Resuscitation
The Surviving Sepsis Guidelines define sepsis as a “life-threatening organ dysfunction caused by a dysregulated host response to an infection”. Septic shock is further defined as sepsis with hypotension (MAP ≤65) and/or lactate ≥2.0 despite adequate fluid...
by Hans Rosenberg | Mar 16, 2020 | Critical Care, Infectious Disease, Journal Club
Methodology: 4/5 Usefulness: 3/5 Fujii T, et al. JAMA. 2020 Jan 17. doi: 10.1001/jama.2019.22176. [Epub ahead of print] Editorial: Lack of Benefit of High-Dose Vitamin C, Thiamine, and Hydrocortisone Combination for Patients With Sepsis. Question and Methods:...
by Shannon Fernando, Kate O'Connell | Jan 30, 2020 | Critical Care, Grand Round Summaries, Resuscitation
In September 2018, Dr. Bram Rochwerg and I wrote a blog post on the treatment of patients with sepsis and septic shock. Much of this was based on the 2016 Surviving Sepsis Campaign (SSc) Clinical Practice Guidelines [1]. However, in a little over a year, significant...
by Hans Rosenberg | Apr 15, 2019 | Critical Care, Full Article, Infectious Disease, Journal Club
Journal Club Summary Methodology: 3/5 Usefulness: 3.5/5 Annane D, et al. N Engl J Med. 2018 Mar 1;378(9):809-818. Editorial: A Role for Hydrocortisone Therapy in Septic Shock? Question and Methods: Large multi-center, double-blinded, randomized-controlled trial...
