by Naman Arora | Oct 1, 2026 | Critical Care, Featured, Grand Round Summaries, Infectious Disease, Resuscitation
Sepsis resuscitation has evolved considerably over the past two decades, moving away from rigid protocols toward more individualized care. Yet many familiar targets remain: 30 mL/kg of fluid, a MAP of 65, and lactate clearance. But not every patient benefits from more...
by Shane Baistrocchi | Sep 17, 2026 | Critical Care, Featured, Grand Round Summaries, Hematology, Immunology, Infectious Disease, Resuscitation
Disseminated intravascular coagulation (DIC) is an acquired, life-threatening disorder characterized by systemic activation of coagulation, dysregulated fibrinolysis, and, as emphasized in the updated definition, endothelial injury. It exists on a continuum, from...
by Sam Wilson, Venkatesh Thiruganasambandamoorthy | Jun 1, 2026 | Critical Care, Journal Club, Resuscitation
Personalized Hemodynamic Resuscitation Targeting Capillary Refill Time in Early Septic Shock: The ANDROMEDA-SHOCK-2 Randomized Clinical Trial. Hernandez G, ANDROMEDA-SHOCK-2 Investigators for the ANDROMEDA Research Network JAMA. 2025 Oct 29:e2520402. doi:...
by James Gilbertson, Hans Rosenberg, Ian Stiell | Apr 9, 2023 | Critical Care, Featured, Infectious Disease, Journal Club, Resuscitation
Methodology: 4/5 Usefulness: 3/5 National Heart, Lung, and Blood Institute Prevention and Early Treatment of Acute Lung Injury Clinical Trials Network; et al. N Engl J Med. 2023 Feb 9;388(6):499-510. doi: 10.1056/NEJMoa2212663. Epub 2023 Jan 21. Question and...
by Doran Drew, Amanda Mattice | Jun 23, 2022 | Critical Care, Featured, Grand Round Summaries, Infectious Disease, Resuscitation
A review of some of the most relevant elements of the 2021 surviving sepsis campaign for the emergency physician. Definitions Our operative definition of sepsis & septic shock are the sepsis-3 definitions [1]. Sepsis: “Sepsis is a life threatening organ...
