by Sam Wilson, Venkatesh Thiruganasambandamoorthy | Jun 1, 2026 | Critical Care, Journal Club, Resuscitation
Personalized Hemodynamic Resuscitation Targeting Capillary Refill Time in Early Septic Shock: The ANDROMEDA-SHOCK-2 Randomized Clinical Trial. Hernandez G, ANDROMEDA-SHOCK-2 Investigators for the ANDROMEDA Research Network JAMA. 2025 Oct 29:e2520402. doi:...
by James Gilbertson, Hans Rosenberg, Ian Stiell | Apr 9, 2023 | Critical Care, Featured, Infectious Disease, Journal Club, Resuscitation
Methodology: 4/5 Usefulness: 3/5 National Heart, Lung, and Blood Institute Prevention and Early Treatment of Acute Lung Injury Clinical Trials Network; et al. N Engl J Med. 2023 Feb 9;388(6):499-510. doi: 10.1056/NEJMoa2212663. Epub 2023 Jan 21. Question and...
by Doran Drew, Amanda Mattice | Jun 23, 2022 | Critical Care, Featured, Grand Round Summaries, Infectious Disease, Resuscitation
A review of some of the most relevant elements of the 2021 surviving sepsis campaign for the emergency physician. Definitions Our operative definition of sepsis & septic shock are the sepsis-3 definitions [1]. Sepsis: “Sepsis is a life threatening organ...
by Hans Rosenberg | Dec 7, 2020 | Critical Care, Featured, Infectious Disease, Journal Club
Methodology: 3.5/5 Usefulness: 3.5/5 Ann Intern Med. 2019 Oct 15;171(8):547-554. Cheng MP, et al. Question and Methods: Multi-center diagnostic study that investigated the sensitivity of post-antimicrobial blood cultures compared to pre-antimicrobial blood cultures in...
by Garrick Mok, Pascale King | May 7, 2020 | Critical Care, Featured, Grand Round Summaries, Infectious Disease, Resuscitation
The Surviving Sepsis Guidelines define sepsis as a “life-threatening organ dysfunction caused by a dysregulated host response to an infection”. Septic shock is further defined as sepsis with hypotension (MAP ≤65) and/or lactate ≥2.0 despite adequate fluid...
