by Kate O'Connell, Hans Rosenberg | Dec 6, 2021 | Cardiology, Critical Care, Journal Club
Methodology: 3.5/5 Usefulness: 3.5/5 Mathew R, et al. N Engl J Med. 2021 Aug 5;385(6):516-525. Question and Methods: The authors performed a double-blinded RCT to determine if milrinone was superior to dobutamine for the treatment of cardiogenic shock in the ICU. ...
by Doran Drew, Josee Malette, Kate O'Connell | May 20, 2021 | Featured, Grand Round Summaries, Neurology, Thrombosis
Review of the formative literature of our current tPA time window in Acute Ischemic Stroke After numerous case series and smaller prospective studies suggesting benefit for thrombolytic therapy (tPA), the early 90s ushered in the era of thrombolytic RCTs for acute...
by Michael Hale, Kate O'Connell | Nov 5, 2020 | Featured, Grand Round Summaries, Neurosurgery, Radiology
The diagnosis of subarachnoid hemorrhage (SAH) carries with it remarkable morbidity and mortality. Case fatality rates approach 50% 1,2 Of those who survive, half will experience chronic disability and a significant reduction in health-related quality of...
by Darren Wong, Kate O'Connell | Aug 6, 2020 | Featured
Case: You are the emergency physician taking care of a 45-year-old male who has a background history of hypertension and dyslipidemia for which he is on a ACEi and a statin. He presents with 2.5 hours of ongoing non-radiating chest discomfort while at work. His...
by Lindsay Cheskes, Kate O'Connell | May 21, 2020 | cardiac arrest, Cardiology, Critical Care, Featured, Grand Round Summaries, Resuscitation
This post takes a deep dive into the pathophysiology, presentation and management of electrical storm in the emergency department. The management focuses on patients with implantable cardioverter-defibrillators receiving multiple shocks, patients with polymorphic...
