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Milrinone as Compared with Dobutamine in the Treatment of Cardiogenic Shock

Milrinone as Compared with Dobutamine in the Treatment of Cardiogenic Shock

by Kate O'Connell, Hans Rosenberg | Dec 6, 2021 | Cardiology, Critical Care, Journal Club

Methodology: 3.5/5 Usefulness: 3.5/5 Mathew R, et al. N Engl J Med. 2021 Aug 5;385(6):516-525. Question and Methods: The authors performed a double-blinded RCT to determine if milrinone was superior to dobutamine for the treatment of cardiogenic shock in the ICU.  ...
Thrombolytic Therapy: A Stroke of Luck? Part 1

Thrombolytic Therapy: A Stroke of Luck? Part 1

by Doran Drew, Josee Malette, Kate O'Connell | May 20, 2021 | Featured, Grand Round Summaries, Neurology, Thrombosis

Review of the formative literature of our current tPA time window in Acute Ischemic Stroke  After numerous case series and smaller prospective studies suggesting benefit for thrombolytic therapy (tPA), the early 90s ushered in the era of thrombolytic RCTs for acute...
Subarachnoid Hemorrhage in the ED- What a Headache!

Subarachnoid Hemorrhage in the ED- What a Headache!

by Michael Hale, Kate O'Connell | Nov 5, 2020 | Featured, Grand Round Summaries, Neurosurgery, Radiology

  The diagnosis of subarachnoid hemorrhage (SAH) carries with it remarkable morbidity and mortality. Case fatality rates approach 50% 1,2 Of those who survive, half will experience chronic disability and a significant reduction in health-related quality of...
High Sensitivity Cardiac Troponin Testing (hs-cTnT) in ACS

High Sensitivity Cardiac Troponin Testing (hs-cTnT) in ACS

by Darren Wong, Kate O'Connell | Aug 6, 2020 | Featured

Case: You are the emergency physician taking care of a 45-year-old male who has a background history of hypertension and dyslipidemia for which he is on a ACEi and a statin. He presents with 2.5 hours of ongoing non-radiating chest discomfort while at work. His...
Braving the Electrical Storm in the ED

Braving the Electrical Storm in the ED

by Lindsay Cheskes, Kate O'Connell | May 21, 2020 | cardiac arrest, Cardiology, Critical Care, Featured, Grand Round Summaries, Resuscitation

This post takes a deep dive into the pathophysiology, presentation and management of electrical storm in the emergency department. The management focuses on patients with implantable cardioverter-defibrillators receiving multiple shocks, patients with polymorphic...
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