by Naman Arora | Jan 9, 2025 | Critical Care, Endocrinology, Featured, Grand Round Summaries, Infectious Disease
In the acute care setting, steroids have various usages and indications, but their usage can often be nuanced. From adrenal crises to septic shock, severe community-acquired pneumonia, and even acute pharyngitis, steroids play a pivotal role in managing a variety of...
by Connor Inglis, Josee Malette | May 30, 2024 | Featured, Prehospital and Transport Medicine, PTM Journal Club
At this month’s PTM Journal Club, we explored the use of high-dose glucocorticoid on hemodynamics in the prehospital setting; in particular, the STEROHCA trial conducted in Denmark. Effect of prehospital high-dose glucocorticoid on hemodynamics in patients...
by Kevin Guo, Hans Rosenberg, Krishan Yadav | May 3, 2023 | Critical Care, Featured, Infectious Disease, Journal Club, Resuscitation
Methodology: 4/5 Usefulness: 4/5 Dequin PF, et al. N Engl J Med. 2023 Mar 21. doi: 10.1056/NEJMoa2215145. Question and Methods: Pneumosepsis can lead to pulmonary and systemic inflammation that can increase risk of organ failure and death. The authors attempted to...
by Kevin Durr, Jeff Perry, Hans Rosenberg | Jan 24, 2022 | Full Article, Infectious Disease, Journal Club
Methodology: 3.5/5 Usefulness: 3.5/5 COVID STEROID 2 Trial Group, Munch MW, et al. JAMA. 2021 Nov 9;326(18):1807-1817. doi: 10.1001/jama.2021.18295. Question and Methods: This blinded randomized clinical trial compared the effects of 12 mg daily relative to 6 mg daily...
by Hans Rosenberg | Sep 27, 2021 | Journal Club, Respirology
Methodology: 4/5 Usefulness: 4.5/5 Dobler CC, et al. Ann Intern Med. 2020 Mar 17;172(6):413-422. Questions & Methods: Systematic review of 68 English language RCTs of outpatient/non ICU inpatients with COPDE comparing pharmacologic therapy with placebo/...
