by Kate O'Connell, Hans Rosenberg | Dec 6, 2021 | Cardiology, Critical Care, Journal Club
Methodology: 3.5/5 Usefulness: 3.5/5 Mathew R, et al. N Engl J Med. 2021 Aug 5;385(6):516-525. Question and Methods: The authors performed a double-blinded RCT to determine if milrinone was superior to dobutamine for the treatment of cardiogenic shock in the ICU. ...
by Maeghan Fu, Hans Rosenberg | Nov 29, 2021 | Journal Club
Methodology: 2.5/5 Usefulness: 3/5 Lin J, et al. Am J Emerg Med. 2021 Jun;44:306-311. Question and Methods: Open-label prospective study comparing the efficacy and safety of ketamine versus haloperidol plus lorazepam in the treatment of acute combative agitation in...
by Hans Rosenberg | Nov 7, 2021 | Featured, Journal Club, Neurology
Methodology: 2.5 5 Usefulness: 2.5/5 Grotta JC, et al. N Engl J Med. 2021 Sep 9;385(11):971-981. doi: 10.1056/NEJMoa2103879. Question and Methods: This study investigated if mobile stroke units (MSU) alter outcomes when compared to standard management by emergency...
by Chirag Bhat, Hans Rosenberg | Nov 2, 2021 | cardiac arrest, Cardiology, Critical Care, Journal Club
Methodology: 4/5 Usefulness: 4/5 Desch S, et al. N Engl J Med. 2021 Aug 29. doi: 10.1056/NEJMoa2101909. Question and Methods: This multi-center, open label RCT of 558 patients with OHCA without ST elevation on their ECG compared 30-day all-cause mortality...
by Darren Wong, Hans Rosenberg | Oct 25, 2021 | Full Article, Infectious Disease, Journal Club
Methodology: 1/5 Usefulness: 1/5 von Dach E, et al. JAMA. 2020 Jun 2;323(21):2160-2169. doi: 10.1001/jama.2020.6348. Question and Methods: In a multi-center, noninferiority, randomized, double-blinded clinical trial, the authors compared the rates of...
by Hans Rosenberg | Oct 11, 2021 | Critical Care, Journal Club, Respirology
Methodology: 4/5 Usefulness: 3/5 Schjørring OL, et al. N Engl J Med. 2021 Apr 8;384(14):1301-1311. doi: 10.1056/NEJMoa2032510. Question and Methods: Can a lower PaO2 target (i.e., 60mmHg) compared to higher PaO2 target (i.e., 90mmHg) decrease all cause 90...
by Hans Rosenberg | Oct 4, 2021 | Featured, Journal Club, Neurology
Methodology: 4/5 Usefulness: 4/5 Perry JJ, et al. BMJ. 2021 Feb 4;372:n49. doi: 10.1136/bmj.n49. Question and methods: This multicenter prospective cohort study validates the Canadian TIA Score and compares it to the ABCD2 and ABCD2i score to identify risk...
by Hans Rosenberg | Sep 27, 2021 | Journal Club, Respirology
Methodology: 4/5 Usefulness: 4.5/5 Dobler CC, et al. Ann Intern Med. 2020 Mar 17;172(6):413-422. Questions & Methods: Systematic review of 68 English language RCTs of outpatient/non ICU inpatients with COPDE comparing pharmacologic therapy with placebo/...
by Hans Rosenberg | Jul 26, 2021 | Full Article, Infectious Disease, Journal Club, landmark, Public health
Methodology: 4/5 Usefulness: 4.5/5 Polack FP, et al. N Engl J Med. 2020 Dec 31;383(27):2603-2615. doi: 10.1056/NEJMoa2034577. Epub 2020 Dec 10. Editorial: SARS-CoV-2 Vaccination – An Ounce (Actually, Much Less) of Prevention. Question/methods: Multinational,...
by Hans Rosenberg | Jul 19, 2021 | Infectious Disease, Journal Club, Pediatrics
Methodology: 3/5 Usefulness: 1/5 Mas-Dalmau G, et al. Pediatrics. 2021 Mar;147(3):e20201323. doi: 10.1542/peds.2020-1323. Question and Methods: This RCT assessed effectiveness and safety of delayed (DAP), immediate (IAP) and no antibiotic prescription (NAP) in...
