by Krishan Yadav | Jan 6, 2022 | Commentary, Featured, Journal Club
Sotrovimab Sotrovimab is a monoclonal antibody that neutralizes sarbecoviruses (respiratory viruses detected by PCR on oral/nasal swabs or from bronchial/lung/respiratory tract specimens). This antibody was first isolated from a patient with SARS-CoV-1 (the virus...
by Hans Rosenberg | Jul 26, 2021 | Full Article, Infectious Disease, Journal Club, landmark, Public health
Methodology: 4/5 Usefulness: 4.5/5 Polack FP, et al. N Engl J Med. 2020 Dec 31;383(27):2603-2615. doi: 10.1056/NEJMoa2034577. Epub 2020 Dec 10. Editorial: SARS-CoV-2 Vaccination – An Ounce (Actually, Much Less) of Prevention. Question/methods: Multinational,...
by Hans Rosenberg | Jun 14, 2021 | COVID-19, Infectious Disease, Journal Club, Respirology
Methodology: 2.5/5 Usefulness: 2/5 Ramakrishnan S, et al. Lancet Respir Med. 2021 Apr 9:S2213-2600(21)00160-0. Question and Methods: Is inhaled budesonide an effective treatment for patients with mild early symptoms of COVID-19? A randomized, open-label clinical trial...
by Darren Wong, Josee Malette | Jun 10, 2021 | cardiac arrest, Critical Care, Featured, Grand Round Summaries, Resuscitation
In the first part of this series, we looked at the basics of Extra Corporeal Membrane Oxygenation (ECMO) and its primary indications. In this section, we will discuss the factors that are needed to implement an ED ECMO program and what happens when a code ECPR is...
by Darren Wong, Josee Malette | Jun 3, 2021 | Grand Round Summaries, Respirology, Resuscitation
Extra Corporeal Membrane Oxygenation (ECMO) has significantly progressed over the past decades. It has become an invaluable tool in the care of adults with severe cardiac and pulmonary disease refractory to conventional management. The implementation of ECMO has even...