by Grace Northrop, Ian Stiell | May 18, 2026 | Anesthesiology, Featured, Journal Club, Pain Medicine
Comparison of inhalational methoxyflurane, intranasal fentanyl, and intravenous morphine for treatment of prehospital acute pain in Norway (PreMeFen): a randomised, non-inferiority, three-arm, phase 3 trial Simensen R, et al. Lancet. 2025 Dec 20;406(10522):2957-2967....
by Emily Cino, Ian Stiell | May 13, 2026 | Gastroenterology, Journal Club
Efficacy and Safety of Pharmacologic Therapies for Nausea and Emesis in the Emergency Department: A Systematic Review and Bayesian Network Meta-analysis. deSouza IS, et al. Ann Emerg Med. 2025 Dec;86(6):646-658. doi: 10.1016/j.annemergmed.2025.06.009. Methodology:...
by Lucy Karp, Christian Vaillancourt | Apr 27, 2026 | Critical Care, Featured, Journal Club
A Crossover Trial of Hospital-Wide Lactated Ringer’s Solution versus Normal Saline McIntyre L, et al. Canadian Critical Care Trials Group. A Crossover Trial of Hospital-Wide Lactated Ringer’s Solution versus Normal Saline. N Engl J Med. 2025 Aug...
by Mathieu McKinnon, Jeff Perry, Shahbaz Syed | Mar 3, 2026 | Featured, Journal Club
Methodology: 4/5 Usefulness: 4/5 N Engl J Med. 2025 Dec 9. doi: 10.1056/NEJMoa2511420. Question and Methods: This multi-center, open label RCT of 2359 patients compared 28-day mortality in patients randomized to receiving ketamine or etomidate for their sedation prior...
