by Sam Wilson, Venkatesh Thiruganasambandamoorthy | Jun 1, 2026 | Critical Care, Journal Club, Resuscitation
Personalized Hemodynamic Resuscitation Targeting Capillary Refill Time in Early Septic Shock: The ANDROMEDA-SHOCK-2 Randomized Clinical Trial. Hernandez G, ANDROMEDA-SHOCK-2 Investigators for the ANDROMEDA Research Network JAMA. 2025 Oct 29:e2520402. doi:...
by Grace Northrop | May 28, 2026 | Featured
Acute Liver Failure (ALF) is rare, with an estimated incidence of 1–6 cases per million per year in Western countries¹². Despite its rarity, it carries significant morbidity and mortality¹. ALF most often affects previously healthy adults in their 30s; in North...
by Stephen Hale, Venkatesh Thiruganasambandamoorthy | May 27, 2026 | Journal Club, Resuscitation
A Randomized Trial of Shared Decision-Making in Code Status Discussions Becker C, et al. NEJM Evid. 2025 May;4(5):EVIDoa2400422. doi: 10.1056/EVIDoa2400422. Methodology: 3.5/5 Usefulness: 3.5/5 Question and Methods: This multi-centre cluster-RCT...
by Meehan Andrew, Venkatesh Thiruganasambandamoorthy | May 25, 2026 | Journal Club, Neurology
Tenecteplase versus standard medical treatment for basilar artery occlusion within 24 h (TRACE-5): a multicentre, prospective, randomised, open-label, blinded-endpoint, superiority, phase 3 trial Xiong Y, Et al. Lancet. 2026 Feb 21;407(10530):763-772. doi:...
by Fiona Raymond, Ian Stiell | May 20, 2026 | ENT, Featured, Journal Club, Neurology
Diagnostic accuracy of the STANDING algorithm in patients with isolated vertigo: a multicentre prospective study (STANDING-M). Ronchetti M,et al. Emerg Med J. 2025 Nov 21;42(12):791-797. doi: 10.1136/emermed-2025-214902. Methodology: 4/5 Usefulness: 2.5/5 Question...
