by Emma Ferguson, Hans Rosenberg, Ian Stiell | Sep 26, 2022 | Journal Club, Neurology
Methodology: 4.5/5 Usefulness: 5/5 Menon BK, et al. Lancet. 2022 Jul 16;400(10347):161-169. doi: 10.1016/S0140-6736(22)01054-6. Question and Methods: This multicentre, open label, randomized control trial at 22 primary and comprehensive stroke centres across Canada...
by Emma Ferguson, Lucy Karp | Sep 1, 2022 | Featured, Neurology, Neurosurgery
Acute stroke care is integrated into emergency medicine in many emergency departments across Canada. Whether you are involved in acute stroke care through consultation with neurology or through tele-stroke, understanding the complications of acute stroke therapy and...
by Doran Drew | Jun 8, 2021 | Commentary, Critical Care, Grand Round Summaries, Journal Club, Resuscitation
Hey everyone! Buckle up. This is a long one. To provide context, I recently presented a 2-part blog post regarding thrombolytics in acute ischemic stroke. In these posts I explored the foundational literature for this tPA, as well as some of the common controversies I...
by Doran Drew, Josee Malette | May 27, 2021 | Featured, Grand Round Summaries, Neurology, Thrombosis
Addressing the Controversies Around Thrombolytic Therapy (tPA) In our previous blog post, we reviewed the formative literature supporting the currently used tPA time window. The figure below highlights a summary of the time windows investigated within each study and...
by Doran Drew, Josee Malette, Kate O'Connell | May 20, 2021 | Featured, Grand Round Summaries, Neurology, Thrombosis
Review of the formative literature of our current tPA time window in Acute Ischemic Stroke After numerous case series and smaller prospective studies suggesting benefit for thrombolytic therapy (tPA), the early 90s ushered in the era of thrombolytic RCTs for acute...