Effect of Nebulized Magnesium vs Placebo Added to Albuterol on Hospitalization Among Children With Refractory Acute Asthma Treated in the Emergency Department: A Randomized Clinical Trial
Methodology: 4.5/5 Usefulness: 4/5 Schuh S, et al. JAMA. 2020 Nov 24;324(20):2038-2047. Question and Methods: RCT assessing the effectiveness of nebulized magnesium... Read more.
Plaster cast versus functional brace for non-surgical treatment of Achilles tendon rupture (UKSTAR): a multicentre randomised controlled trial and economic evaluation
Methodology: 3.5/5 Usefulness: 3.5/5 Costa ML et al. Lancet. 2020 Feb 8;395(10222):441-448. Question and Methods: The UKSTAR trial was a pragmatic, multicenter RCT... Read more.
Hyoscine butylbromide versus acetaminophen for nonspecific colicky abdominal pain in children: a randomized controlled trial
Methodology: 4/5 Usefulness: 1/5 Poonai N, et al. CMAJ. 2020 Nov 30;192(48):E1612-E1619. Question and Methods: Randomized control trial assessing effect of hyoscine... Read more.
Mifepristone and misoprostol versus misoprostol alone for the management of missed miscarriage (MifeMiso): a randomised, double-blind, placebo-controlled trial
Methodology: 4/5 Usefulness: 3/5 Chu JJ, et al. Lancet. 2020 Sep 12;396(10253):770-778. Editorial: Medical management of miscarriage with mifepristone Question and... Read more.
Blunt cerebrovascular injury: The case for universal screening.
Methodology: 2/5 Usefulness: 4/5 Leichtle SW, et al. J Trauma Acute Care Surg. 2020 Nov;89(5):880-886. Question and Methods: Existing BCVI screening guidelines... Read more.
Prospective Implementation of the Ottawa Subarachnoid Hemorrhage Rule and 6-Hour Computed Tomography Rule
Methodology: 4/5 Usefulness: 4/5 Perry JJ, et al. Stroke. 2020 Feb;51(2):424-430. doi: 10.1161/STROKEAHA.119.026969. Question and Methods: Prospective, multi-center... Read more.
Antibiotics Do Not Reduce Length of Hospital Stay for Uncomplicated Diverticulitis in a Pragmatic Double-Blind Randomized Trial
Methodology: 2/5 Usefulness: 2/5 Jaung R, et al. Clin Gastroenterol Hepatol. 2020 Mar 30:S1542-3565(20)30426-2. Question and Methods: This study investigated non-inferiority... Read more.
Ambulatory management of primary spontaneous pneumothorax: an open-label, randomised controlled trial
Methodology: 4/5 Usefulness: 3/5 Hallifax RJ, et al. Lancet. 2020 Jul 4;396(10243):39-49. Question and Methods: This multicentre open label randomized control trial... Read more.
Timing of Endoscopy for Acute Upper Gastrointestinal Bleeding
Methodology: 3/5 Usefulness: 3.5/5 Lau JYW, et al. N Engl J Med. 2020 Apr 2;382(14):1299-1308. Question and Methods: Single centre RCT comparing whether urgent (<6h)... Read more.
Blood Culture Results Before and After Antimicrobial Administration in Patients With Severe Manifestations of Sepsis: A Diagnostic Study
Methodology: 3.5/5 Usefulness: 3.5/5 Ann Intern Med. 2019 Oct 15;171(8):547-554. Cheng MP, et al. Question and Methods: Multi-center diagnostic study that investigated... Read more.