by Hans Rosenberg | Feb 24, 2020 | Anesthesiology, Journal Club
Methodology: 2/5 Usefulness: 2.5 /5 Lumanauw DD, et al. Acad Emerg Med. 2019 Sep;26(9):1044-1051. doi: 10.1111/acem.13755. Epub 2019 Apr 29. Question and Methods: A randomized placebo-controlled trial to determine if sub-dissociative dose Ketamine (SDDK) is effective...
by Hans Rosenberg | Feb 17, 2020 | Infectious Disease, Journal Club, Respirology
Methodology: 4/5 Usefulness: 2/5 Alexander E., et al. JAMA. 2019 Sep 27. doi: 10.1001/jama.2019.15468. Editorial: Lefamulin-A New Antibiotic for Community-Acquired Pneumonia. Question and Methods: LEAP-2 was a phase 3, double-blinded RCT to determine non-inferiority...
by Hans Rosenberg | Feb 10, 2020 | Journal Club, landmark, Thrombosis
Methodology Score: 4/5 Usefulness Score: 4.5/5 Kearon C, et al. N Engl J Med. 2019 Nov 28;381(22):2125-2134 Question and Methods: the authors sought to demonstrate safety using a d-dimer cut-off of 1000ng/mL for low pre-test probability patients & a cut-off of...
by Hans Rosenberg | Feb 3, 2020 | Full Article, Journal Club, Trauma
Methodology: 4/5 Usefulness: 2/5 Sims CA, et al. JAMA Surg. 2019 Aug 28. Question and Methods: Single-centre, double-blind, randomized control trial to determine whether low-dose vasopressin decreases the need for blood product transfusion in trauma patients with...
by Shahbaz Syed | Jan 31, 2020 | Cardiology, Featured, Infographics, Journal Club
RAFF2 Ian Stiell and colleagues are back at it with atrial fibrillation; The RAFF2 trial (Electrical versus Chemical cardioversion for Emergency Department patients with Atrial Fibrillation (RAFF2); A partial factorial randomized trial) was published in The Lancet...
by Hans Rosenberg | Jan 27, 2020 | Full Article, Journal Club, Pediatrics
Methodology: 4/5 Usefulness: 4/5 Lyttle MD, et al. Lancet. 2019 May 25;393(10186):2125-2134. Question and Methods: Eclipse was an open label RCT that evaluated time to seizure cessation in pediatric SE between Keppra and Dilantin Findings: They found that Keppra was...
by Hans Rosenberg | Dec 16, 2019 | Full Article, Journal Club, Neurosurgery, Resuscitation, Trauma
Methodology Score: 3/5 Usefulness Score: 3/5 Cooper DJ, et al. JAMA. 2018;320(21):2211-2220. doi:10.1001/jama.2018.17075 Question/Methods: This study was done to determine the effectiveness of early prophylactic hypothermia compared with normothermic management of...
by Hans Rosenberg | Dec 2, 2019 | Journal Club, Orthopedics, Orthopedics, Trauma
Methodology: 4/5 Usefulness: 3.5/5 Kortekangas T, et al. BMJ. 2019 Jan 23;364:k5432 Question and Methods: This is a pragmatic, randomized, controlled trial to determine if 3 weeks of immobilization (in cast or orthosis) is non-inferior to usual treatment (6 weeks cast...
by Krishan Yadav | Nov 7, 2019 | Featured, Journal Club, Trauma
Dr. Krishan Yadav is an FRCPC Emergency Medicine Physician with a Masters in Clinical Epidemiology, and here he helps to provide some great insights and opinions into the recently published CRASH-3 trial. Tranexamic Acid (TXA) TXA is an inexpensive and readily...
by Hans Rosenberg | Oct 14, 2019 | ENT, Journal Club
Methodology Score: 2.5/5 Usefulness Score: 2.5/5 Akkan S, et al. Ann Emerg Med. 2019 Jul;74(1):72-78 Question and Methods: Prospective RCT comparing compression with saline, compression with tranexamic acid, and nasal packing with merocel for anterior epistaxis....
