Early and Empirical High-Dose Cryoprecipitate for Hemorrhage After Traumatic Injury: The CRYOSTAT-2 Randomized Clinical Trial

Early and Empirical High-Dose Cryoprecipitate for Hemorrhage After Traumatic Injury: The CRYOSTAT-2 Randomized Clinical Trial

by , , | Nov 22, 2023 | Featured, Full Article, Hematology, Journal Club, Trauma

Methodology: 3.5/5 Usefulness: 4/5 Davenport R, et al. JAMA. 2023 Oct 12:e2321019.  Editorial: Contemporary Adjuncts to Hemorrhage Control. Question and Methods: In trauma patients with major hemorrhage, does early cryoprecipitate (6g fibrinogen) administration...
The third Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT3): an international, stepped wedge cluster randomised controlled trial

The third Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT3): an international, stepped wedge cluster randomised controlled trial

by , , | Nov 6, 2023 | Critical Care, Full Article, Journal Club, Neurology

Methodology: 4/5 Usefulness: 4/5 Ma L, et al. Lancet 2023 Jul 1;402(10395):27-40. Question and Methods: Do 6 month outcomes improve after implementation of a goal-directed care bundle that corrects prognostically poor physiological abnormalities (systolic...
Reduction of urea test ordering in the emergency department: multicomponent intervention including education, electronic ordering, and data feedback

Reduction of urea test ordering in the emergency department: multicomponent intervention including education, electronic ordering, and data feedback

by , , | Jul 4, 2023 | Journal Club, Quality Improvement

Methodology: 2.5/5 Usefulness: 2/5 Mathura P, et al. CJEM. 2022 Sep;24(6):636-640. Editorial: When evidence-based medicine and quality improvement collide. Question and Methods: Can we decrease physician ordering of the BUN (blood urea nitrogen) test, using an...
Efficacy and Safety of Early Administration of 4-Factor Prothrombin Complex Concentrate in Patients With Trauma at Risk of Massive Transfusion: The PROCOAG Randomized Clinical Trial

Efficacy and Safety of Early Administration of 4-Factor Prothrombin Complex Concentrate in Patients With Trauma at Risk of Massive Transfusion: The PROCOAG Randomized Clinical Trial

by , , | Jun 19, 2023 | Featured, Journal Club, Thrombosis, Trauma

Methodology: 4/5 Usefulness: 3.5/5 Bouzat P, et al. JAMA. 2023 Mar 21:e234080. doi: 10.1001/jama.2023.4080.  Question and Methods:  This double-blind, randomized, placebo-controlled superiority trial aimed to assess whether 4F-PCC decreases 24hr blood product...
Quality initiative to improve emergency department sepsis bundle compliance through utilisation of an electronic health record tool

Quality initiative to improve emergency department sepsis bundle compliance through utilisation of an electronic health record tool

by , , | Jun 12, 2023 | Featured, Full Article, Journal Club, Quality Improvement

Methodology: 2/5 Usefulness: 3/5 Warstadt NM, et al. BMJ Open Qual. 2022 Jan;11(1):e001624. Questions and Methods: Using a cohort and QI approach, to demonstrate the effectiveness of a multidisciplinary educational intervention and EHR tool to increase sepsis bundle...
Safely reducing abdominal/pelvic computed tomography imaging in pediatric trauma: a quality improvement initiative

Safely reducing abdominal/pelvic computed tomography imaging in pediatric trauma: a quality improvement initiative

by , , | Jun 5, 2023 | Featured, Full Article, Journal Club, Pediatrics, Trauma

Methodology: 4.5/5 Usefulness: 5/5 Beno S, al. CJEM. 2022 Aug;24(5):535-543.  Editorial: Reducing overuse of CT imaging in pediatric trauma: a model example of the Model for Improvement. Question and Methods: The aim  of this QI project was to reduce unnecessary CT...