We are excited to introduce the Sixth edition of The Ottawa Handbook of Emergency Medicine. Your bedside guide for approaches to various Emergency Medicine presentations.
Highlights of the Sixth edition include the addition of: Oncologic emergencies, approach to the pregnant patient, geriatrics and more!
Meta-analysis of Usefulness of D-dimer to Diagnose Acute Aortic Dissection
Journal Club Summary Methodology Score: 3/5 Usefulness Score: 3/5 Shimony A, Filion KB, Mottillo S, Dourian T, Eisenberg MJ. Am J Cardiol. 2011 Apr 15;107(8):1227-34 Abstract Link This meta-analysis of seven studies shows a pooled sensitivity...
Lactate Clearance vs Central Venous Oxygen Saturation as Goals of Early Sepsis Therapy: a Randomized Clinical Trial
Journal Club Summary Methodology Score: 3.5/5 Usefulness Score: 3.5/5 Jones AE, Shapiro NI, Trzeciak S, Arnold RC, Claremont HA, Kline JA; Emergency Medicine Shock Research Network (EMShockNet) Investigators. JAMA. 2010 Feb 24;303(8):739-46. Article...
Transfusion Strategies for Acute Upper Gastrointestinal Bleeding
Journal Club Summary Landmark Series Methodology Score: 3.5/5 Usefulness Score: 4/5 Villanueva C, Colomo A, Bosch A, Concepción M, Hernandez-Gea V, Aracil C, Graupera I, Poca M, Alvarez-Urturi C, Gordillo J, Guarner-Argente C, Santaló M, Muñiz E,...
Oral Dimenhydrinate versus Placebo in Children with Gastroenteritis: a Randomized Controlled Trial
Journal Club Summary Methodology Score: 2.5/5 Usefulness Score: 2/5 Gouin S, Vo TT, Roy M, Lebel D, Gravel J. Pediatrics. 2012 Jun;129(6):1050-5. Article Link This randomized, double-blinded, placebo-controlled trial of 144 children in Montreal...
Diuretic Strategies in Patients with Acute Decompensated Heart Failure
Journal Club Summary Methodology: 3.5/5 Usefulness: 2/5 Felker GM, et al. NHLBI Heart Failure Clinical Research Network. N Engl J Med. 2011 Mar 3;364(9):797-805 Article Link This double-blind double-dummy RCT (N=308) found that there was no difference in the patient...
Subclinical cerebral edema in children with diabetic ketoacidosis randomized to 2 different rehydration protocols
Journal Club Summary Methodology Score: 2/5 Usefulness Score: 2/5 Glaser NS, Wootton-Gorges SL, Buonocore MH, Tancredi DJ, Marcin JP, Caltagirone R, Lee Y, Murphy C, Kuppermann N. Pediatrics. 2013 Jan;131(1):e73-80 Abstract Link This pilot randomized controlled...
Parenteral dexamethasone for acute severe migraine headache: meta-analysis of randomised controlled trials for preventing recurrence
Journal Club Summary Landmark Article Series Methodology Score: 4.5/5 Usefulness Score: 4.5/5 Colman I, Friedman BW, Brown MD, Innes GD, Grafstein E, Roberts TE, Rowe BH. BMJ. 2008 Jun 14;336(7657):1359-61 Article Link In this well performed meta-analysis, a...
Fibrinolysis or Primary PCI in ST-Segment Elevation Myocardial Infarction
Journal Club Summary Methodology Score: 3.5/5 Usefulness Score: 2.5/5 Armstrong PW, et al. STREAM Investigative Team. N Engl J Med. 2013 Apr 11;368(15):1379-87 Abstract Link This open-label, prospective, randomized, parallel, comparative, international...
Moderate Pulmonary Embolism Treated With Thrombolysis (from the “MOPETT” Trial)
Journal Club Summary Methodology Score: 3.5/5 Usefulness Score: 1.5/5 Sharifi M, Bay C, Skrocki L, Rahimi F, Mehdipour M; “MOPETT” Investigators. Am J Cardiol. 2013 Jan 15;111(2):273-7 Article Link This single-center, open label, randomized control...
Cast versus splint in children with minimally angulated fractures of the distal radius: a randomized controlled trial.
Journal Club Summary Methodology Score: 3/5 Usefulness Score: 4/5 Boutis K, Willan A, Babyn P, Goeree R, Howard A. CMAJ. 2010 Oct 5;182(14):1507-12. Article Link This non-blinded, single-center RCT (N=96) of children aged 5-12 with minimally...
