by Daniel Czikk, Hans Rosenberg, Venkatesh Thiruganasambandamoorthy | Dec 15, 2025 | Featured, Journal Club, Neurology
Methodology: 4/5 Usefulness: 4/5 Qiu Z, et al. N Engl J Med. 2025 Jul 10;393(2):139-150. doi: 10.1056/NEJMoa2503867. Question and Methods: This multi-center, open-label RCT of 550 patients in China with acute ischemic stroke due to large vessel occlusion presenting...
by Amanda Mattice, Hans Rosenberg, Venkatesh Thiruganasambandamoorthy | Dec 8, 2025 | Journal Club, Urology
Methodology: 4/5 Usefulness: 3.5/5 Toumia M, et al. Ann Emerg Med. 2024 Dec;84(6):670-677. doi: 10.1016/j.annemergmed.2024.06.015. Question and Methods: This double-blinded RCT studied whether using adjuncts including MgSO4 and lidocaine are more effective than NSAID...
by Maria Berliant, Hans Rosenberg, Venkatesh Thiruganasambandamoorthy | Dec 1, 2025 | Full Article, Gastroenterology, Journal Club, Toxicology
Methodology: 3.5/5 Usefulness: 4/5 Isbister G, et al. J Hepatol. 2025 Oct;83(4):881-887. doi: 10.1016/j.jhep.2025.05.008. Question and Methods: This multicentre unblinded RCT with 204 patients assessed non-inferiority of a 12-hour NAC protocol for single non-massive...
by Faran Khalid, Hans Rosenberg, Ian Stiell | Nov 3, 2025 | Full Article, Journal Club, Neurology
Methodology: 3.5/5 Usefulness: 3.5/5 Alexandrov AW, et al. JAMA Neurol. 2025 Sep 1;82(9):905-914. doi: 10.1001/jamaneurol.2025.2253. Question and Methods: Authors aimed to determine if 0° head positioning reduces neurological deterioration and mortality in stroke...
by Kaitlin Endres, Hans Rosenberg, Ian Stiell | Oct 22, 2025 | Journal Club, Neurology
Methodology: 4.5/5 Usefulness: 4/5 Miao Z, et al. JAMA. 2025 Aug 19;334(7):582-591. doi: 10.1001/jama.2025.10800. Question and Methods: To compare clinical outcomes in patients with acute LVO for those who received intra-arterial tenecteplase after successful...
