PECARN prediction rules for CT imaging of children presenting to the emergency department with blunt abdominal or minor head trauma: a multicentre prospective validation study

PECARN prediction rules for CT imaging of children presenting to the emergency department with blunt abdominal or minor head trauma: a multicentre prospective validation study

Methodology: 3/5 Usefulness: 3/5 Holmes JF, et al. Lancet Child Adolesc Health. 2024 May;8(5):339-347.  Question and Methods: This prospective multicenter cohort study sought to validate the PECARN intra-abdominal injury and traumatic brain injury rules in order to...
Derivation of the Falls Decision Rule to exclude intracranial bleeding without head CT in older adults who have fallen

Derivation of the Falls Decision Rule to exclude intracranial bleeding without head CT in older adults who have fallen

Methodology: 3.5/5 Usefulness: 3.5/5 CMAJ. 2023 Dec 3;195(47):E1614-E1621. de Wit K, et al. doi: 10.1503/cmaj.230634.  Question and Methods: The Falls Decision Rule was derived to identify older adults with fall who do not require CT to rule out intracranial bleeding,...
Risk of Traumatic Brain Injuries in Infants Younger than 3 Months With Minor Blunt Head Trauma

Risk of Traumatic Brain Injuries in Infants Younger than 3 Months With Minor Blunt Head Trauma

Methodology: 3/5 Usefulness: 3.5/5 Abid Z, et al. Ann Emerg Med. 2021 Sep;78(3):321-330.e1.  Question and Methods: The study assessed the risk of brain injuries and fractures among infants <3 months with/without PECARN low-risk criteria by secondary analysis of...
Intracranial hemorrhage after head injury among older patients on anticoagulation seen in the emergency department: a population-based cohort study

Intracranial hemorrhage after head injury among older patients on anticoagulation seen in the emergency department: a population-based cohort study

Methodology: 3/5 Usefulness: 3/5 Grewal K, et al. CMAJ. 2021 Oct 12;193(40):E1561-E1567.  Question and Methods: Retrospective cohort study evaluating risk of ICH post head injury in ED patients >65 years on warfarin or DOAC or no anticoagulant. Findings: Patients...
Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomized, placebo-controlled trial

Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomized, placebo-controlled trial

Methodology: 3.5/5 Usefulness: 3.5/5 The CRASH-3 trial collaborators. The Lancet. 2019 Oct 14. Online First Editorial: CRASH-3: a win for patients with traumatic brain injury Question and Methods: Multi-centre, randomized, placebo-controlled trial looking at whether...