by Hans Rosenberg | Mar 18, 2019 | Critical Care, Full Article, Journal Club, landmark, Neurosurgery
Journal Club Methodology Score: 4/5 Usefulness Score: 3/5 Sprigg N, et al. Lancet. 2018 May 26;391(10135):2107-2115 Question and Methods: Multicenter, double-blinded, randomized, placebo-controlled trial comparing if IV TXA vs placebo, given within 8h of spontaneous...
by Katherine Soucie, Richard Hoang, Shankar Sethuraman | Feb 14, 2019 | Featured, Grand Round Summaries
In this post, we will aim to review the literature looking at identifying clinical and historical features that can help differentiate stroke mimics from strokes. We will also discuss the safety of the administration of IV tPA to misdiagnosed stroke mimics. This post...
by emottawa | Sep 7, 2015 | Journal Club
Journal Club Summary Methodology Score: 3/5 Usefulness Score: 3/5 Tsivgoulis G, Katsanos AH, Butcher KS, et al. Neurology. 2014 Oct 21;83(17):1523-9 Abstract Link This systematic review and meta-analysis of 4 RCTs found that mortality rates...
by EMOttawa | Sep 12, 2012 | Journal Club, landmark
Journal Club Summary Landmark Series Mayer SA, Brun NC, Begtrup K, Broderick J, Davis S, Diringer MN, et al. N Engl J Med. 2008 May 15;358(20):21 27–37. Article Link This industry sponsored, international multicentre RCT involved 841 patients with acute ICH and found...