by Evelyn Tran, Hans Rosenberg, Jeff Perry | May 9, 2022 | Journal Club, Neurology
Methodology: 3/5 Usefulness: 2/5 Jovin TG, et al. Lancet. 2022 Jan 15;399(10321):249-258. doi: 10.1016/S0140-6736(21)01341-6. Editorial: Late thrombectomy for ischaemic stroke. Dippel D, et al. Lancet. 2022 Jan 15;399(10321):213-215. Question and Methods: This...
by Renee Bradley, Hans Rosenberg, Jeff Perry | May 2, 2022 | Critical Care, Journal Club, Neurology, Neurosurgery
Methodology: 4.5/5 Usefulness: 4/5 Post R, et al. Lancet. 2021 Jan 9;397(10269):112-118. doi: 10.1016/S0140-6736(20)32518-6. Question and Methods: This prospective, multicentre, randomized, controlled, open-label trial investigated whether administering TXA...
by Doran Drew | Jun 8, 2021 | Commentary, Critical Care, Grand Round Summaries, Journal Club, Resuscitation
Hey everyone! Buckle up. This is a long one. To provide context, I recently presented a 2-part blog post regarding thrombolytics in acute ischemic stroke. In these posts I explored the foundational literature for this tPA, as well as some of the common controversies I...
by Doran Drew, Josee Malette | May 27, 2021 | Featured, Grand Round Summaries, Neurology, Thrombosis
Addressing the Controversies Around Thrombolytic Therapy (tPA) In our previous blog post, we reviewed the formative literature supporting the currently used tPA time window. The figure below highlights a summary of the time windows investigated within each study and...
by Hans Rosenberg | Mar 22, 2021 | Journal Club, Neurology
Methodology: 4/5 Usefulness: 3.5/5 Thomalla G, et al. Lancet. 2020 Nov 14;396(10262):1574-1584 Question and Methods: The authors evaluated the role of perfusion-imaging facilitated thrombolysis in strokes of unknown duration by way of a systematic review and...