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Managing Complications of Acute Stroke Therapy

Managing Complications of Acute Stroke Therapy

by Emma Ferguson, Lucy Karp | Sep 1, 2022 | Featured, Neurology, Neurosurgery

Acute stroke care is integrated into emergency medicine in many emergency departments across Canada. Whether you are involved in acute stroke care through consultation with neurology or through tele-stroke, understanding the complications of acute stroke therapy and...
CNS Compartment Syndrome: Cerebral Venous Thrombosis

CNS Compartment Syndrome: Cerebral Venous Thrombosis

by Evelyn Tran, Alie Wudwud | Feb 18, 2021 | Featured, Grand Round Summaries, Radiology

Cerebral venous thrombosis (CVT) is a thrombotic disease of the cerebral veins and major dural sinuses. It is a rare kind of venous thromboembolism and can also be thought of as a type of stroke. CVT accounts for 0.5-1% of stroke cases. The annual incidence is 0.2 –...
Randomized Trial of Three Anticonvulsant Medications for Status Epilepticus

Randomized Trial of Three Anticonvulsant Medications for Status Epilepticus

by Hans Rosenberg | Mar 2, 2020 | Journal Club, Neurology, Pediatrics

Methodology Score: 4/5 Usefulness Score: 3.5/5 Kapur J et al. N Engl J Med. 2019 Nov 28;381(22):2103-2113.  Question and Methods: A multicenter, randomized, blinded, comparative-effectiveness trial to determine the efficacy and safety of fosphenytoin, valproic acid...
Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial

Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial

by Hans Rosenberg | Jan 27, 2020 | Full Article, Journal Club, Pediatrics

Methodology: 4/5 Usefulness: 4/5 Lyttle MD, et al. Lancet. 2019 May 25;393(10186):2125-2134. Question and Methods: Eclipse was an open label RCT that evaluated time to seizure cessation in pediatric SE between Keppra and Dilantin Findings: They found that Keppra was...

Lorazepam vs diazepam for pediatric status epilepticus: a randomized clinical trial

by emottawa | Oct 20, 2014 | Journal Club

Journal Club Summary Methodology Score: 3/5 Usefulness Score: 2.5/5  Chamberlain JM, et al; Pediatric Emergency Care Applied Research Network (PECARN). JAMA.2014 Apr 23-30;311(16):1652-60. doi: 10.1001/jama.2014.2625. Full Article   This double-blind, multi-center,...
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