by Hans Rosenberg | Apr 27, 2021 | COVID-19, Critical Care, Featured, Full Article, Infectious Disease, Journal Club
Methodology: 4/5 Usefulness: 4/5 WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group, Sterne JAC et al. JAMA. 2020 Oct 6;324(13):1330-1341. Question and Methods: Prospective meta-analysis of 7 RCTs investigating the utility of systemic...
by Hans Rosenberg | Mar 29, 2021 | Full Article, Journal Club, Rheumatology
Methodology: 2/5 Usefulness: 2/5 van der Geest KSM, et al. JAMA Intern Med. 2020 Oct 1;180(10):1295-1304. Question and Methods: Systematic review and meta-analysis of 68 studies to identify clinical and laboratory findings that can help identify patients with GCA...
by Hans Rosenberg | Feb 1, 2021 | Featured, Full Article, Journal Club, Orthopedics
Methodology: 3.5/5 Usefulness: 3.5/5 Costa ML et al. Lancet. 2020 Feb 8;395(10222):441-448. Question and Methods: The UKSTAR trial was a pragmatic, multicenter RCT that compared plaster cast against walking boot for non-operative management of Achilles tendon rupture...
by Hans Rosenberg | Jan 25, 2021 | Chronic Pain, Full Article, Gastroenterology, Journal Club
Methodology: 4/5 Usefulness: 1/5 Poonai N, et al. CMAJ. 2020 Nov 30;192(48):E1612-E1619. Question and Methods: Randomized control trial assessing effect of hyoscine butylbromide (HBB) vs acetaminophen in nonspecific colicky pain in pediatric patients aged 8-17yo....
by Hans Rosenberg | Jan 18, 2021 | Full Article, Journal Club, OBGYN
Methodology: 4/5 Usefulness: 3/5 Chu JJ, et al. Lancet. 2020 Sep 12;396(10253):770-778. Editorial: Medical management of miscarriage with mifepristone Question and Methods: This multi-centre, randomized, double blind, placebo-controlled trial compares spontaneous...
by Hans Rosenberg | Jan 3, 2021 | Full Article, Journal Club, Neurosurgery
Methodology: 4/5 Usefulness: 4/5 Perry JJ, et al. Stroke. 2020 Feb;51(2):424-430. doi: 10.1161/STROKEAHA.119.026969. Question and Methods: Prospective, multi-center before and after study looking at the implementation of the Ottawa Subarachnoid Hemorrhage Rule and...
by Hans Rosenberg | Dec 21, 2020 | Full Article, Journal Club, Respirology
Methodology: 4/5 Usefulness: 3/5 Hallifax RJ, et al. Lancet. 2020 Jul 4;396(10243):39-49. Question and Methods: This multicentre open label randomized control trial aimed to determine whether primary spontaneous pneumothoraces could be safely and effective managed...
by Hans Rosenberg | Dec 14, 2020 | Full Article, Gastroenterology, Journal Club, Resuscitation
Methodology: 3/5 Usefulness: 3.5/5 Lau JYW, et al. N Engl J Med. 2020 Apr 2;382(14):1299-1308. Question and Methods: Single centre RCT comparing whether urgent (<6h) endoscopy improved outcomes compared to early endoscopy (6-24h) in patients presenting with...
by Hans Rosenberg | Nov 2, 2020 | Anesthesiology, Full Article, Journal Club, Resuscitation
Methodology: 3.5/5 Usefulness: 2/5 Turner JS, et al. JAMA Netw Open. 2020 Jul 1;3(7):e209278. Question and Methods: Systematic review and meta-analysis evaluating if checklist use during endotracheal intubation leads to improved patient outcomes. Findings: The authors...
by Hans Rosenberg | Sep 28, 2020 | Full Article, Gastroenterology, Journal Club
Methodology: 4/5 Usefulness: 4/5 HALT-IT Trial Collaborators. Lancet. 2020 Jun 20;395(10241):1927-1936 Questions and Methods: This was an international, randomized, double-blind, placebo-controlled trial with the objective to quantify the effect of TXA on death due to...
