by Hans Rosenberg | Jun 7, 2021 | Featured, Immunology, Infectious Disease, Journal Club
Methodology: 3/5 Usefulness: 2/5 Trubiano JA, et al. JAMA Intern Med. 2020 May 1;180(5):745-752. Question and Methods: Prospective derivation and subsequent retrospective validation of a clinical decision rule for the detection of patients at low risk for true...
by Hans Rosenberg | Apr 27, 2021 | COVID-19, Critical Care, Featured, Full Article, Infectious Disease, Journal Club
Methodology: 4/5 Usefulness: 4/5 WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group, Sterne JAC et al. JAMA. 2020 Oct 6;324(13):1330-1341. Question and Methods: Prospective meta-analysis of 7 RCTs investigating the utility of systemic...
by Hans Rosenberg | Dec 29, 2020 | Gastroenterology, Infectious Disease, Journal Club
Methodology: 2/5 Usefulness: 2/5 Jaung R, et al. Clin Gastroenterol Hepatol. 2020 Mar 30:S1542-3565(20)30426-2. Question and Methods: This study investigated non-inferiority of placebo vs antibiotic in management of uncomplicated diverticulitis by conducting an...
by Hans Rosenberg | Dec 7, 2020 | Critical Care, Featured, Infectious Disease, Journal Club
Methodology: 3.5/5 Usefulness: 3.5/5 Ann Intern Med. 2019 Oct 15;171(8):547-554. Cheng MP, et al. Question and Methods: Multi-center diagnostic study that investigated the sensitivity of post-antimicrobial blood cultures compared to pre-antimicrobial blood cultures in...
by Jessica McCallum, Alex Coutin | Oct 15, 2020 | Featured, Global health, Grand Round Summaries, Infectious Disease, Infectious Disease, Public health, Tropical Medicine
In part one of this two-part series, we took a bite out of Lyme disease and Malaria (see what we did there?). In this part, we’ll be covering African tick-bite fever, African sleeping sickness, Dengue, Chikungunya, and Zika. Fever in the returning traveler is...
by Jessica McCallum, Alex Coutin | Sep 24, 2020 | Featured, Global health, Grand Round Summaries, Infectious Disease, Public health, Tropical Medicine
In part one of a two-part series on vector-borne illnesses, we seek to take a deep dive into Lyme disease and Malaria. For more on the other vector-borne illnesses, check out part two! The only helpful way to distinguish between all these illnesses is the...
by Shahbaz Syed | Sep 17, 2020 | Featured, Infectious Disease
Here we present a STI ‘cheat sheet’ to commonly encountered STIs – their etiology, workup and treatment. The following recommendations are based on the Canadian PHAC guidelines. We will not cover the important aspect of taking a sexual history, but...
by Robert Suttie, Shahbaz Syed | Sep 10, 2020 | Featured, Grand Round Summaries, Infectious Disease
Does diarrhea run in your family? Ok, that one’s bad, we apologize. There is significant practice variation when it comes to acute diarrheal illness – fortunately, there are some recommendations to help guide our practices, and in particular, when we...
by Hans Rosenberg | Jun 29, 2020 | Full Article, Infectious Disease, Infectious Disease, Journal Club, OBGYN
Methodology: 3/5 Usefulness: 2.5/5 Gaydos CA et al. Ann Emerg Med. 2019 Jul;74(1):36-44. doi: 10.1016/j.annemergmed.2018.09.012. Epub 2018 Nov 2. Question and Methods: RCT of women receiving pelvic testing for CT/NG comparing standard of care test (NAAT) vs....
by Garrick Mok, Pascale King | May 7, 2020 | Critical Care, Featured, Grand Round Summaries, Infectious Disease, Resuscitation
The Surviving Sepsis Guidelines define sepsis as a “life-threatening organ dysfunction caused by a dysregulated host response to an infection”. Septic shock is further defined as sepsis with hypotension (MAP ≤65) and/or lactate ≥2.0 despite adequate fluid...
