We are excited to introduce the Sixth edition of The Ottawa Handbook of Emergency Medicine. Your bedside guide for approaches to various Emergency Medicine presentations.
Highlights of the Sixth edition include the addition of: Oncologic emergencies, approach to the pregnant patient, geriatrics and more!
Albumin replacement in patients with severe sepsis or septic shock
Journal Club Summary Methodology Score: 3.5/5 Usefulness Score: 2.5/5 Caironi P, Tognoni G, et al. the ALBIOS Study Investigators. N Engl J Med. 2014 Mar 18. Abstract Link This was an open-label RCT of 1,800 ICU patients with severe sepsis or septic...
Impact Factors for Emergency Medicine and Other Popular Journals
The impact factor (IF) of scientific journal reflects the average number of citations to recent articles published in the journal. It is used as a proxy for the relative importance of a journal, with journals with higher impact factors deemed to be more important...
Accuracy of single progesterone test to predict early pregnancy outcome in women with pain or bleeding: meta-analysis of cohort studies
Journal Club Summary Methodology Score: 4/5 Usefulness Score: 2/5 Verhaegen J, Gallos ID, van Mello NM, Abdel-Aziz M, Takwoingi Y, Harb H, Deeks JJ, Mol BW, Coomarasamy A BMJ. 2012 Sep 27;345:e6077 Article Link This thorough and well performed...
Outpatient versus inpatient treatment for patients with acute pulmonary embolism: an international, open-label, randomised, non-inferiority trial
Journal Club Summary Methodology Score: 4/5 Usefulness Score: 3.5/5 Aujesky D, et al. Lancet. 2011 Jul 2;378(9785):41-8. Abstract Link This open label, randomized, un-blinded, multi-centered trial compared inpatient vs. outpatient treatment of low-risk PE showed...
Fever Control Using External Cooling in Septic Shock: A Randomized Controlled Trial
Journal Club Summary Methodology Score: 2.5/5 Usefulness Score: 2/5 Schortgen F, et al. Am J Respir Crit Care Med. 2012 May 15;185(10):1088-95 Full Article This randomized, non-blinded trial found in an ICU population that external cooling in...
A Randomized Trial of Colchicine for Acute Pericarditis
Journal Club Summary Methodology Score: 4.5/5 Usefulness Score: 4.5/5 Imazio M, et al. ICAP Investigators. N Engl J Med. 2013 Oct 17;369(16):1522-8. Article Link This multicentre double-blind RCT found that a 3 month course of low-dose...
Sensitivity of Bedside Ultrasound and Supine Anteroposterior Chest Radiographs for the Identification of Pneumothorax After Blunt Trauma
Journal Club Summary Landmark Series Methodology Score: 4/5 Usefulness Score: 4/5 Wilkerson RG, Stone MB. Acad Emerg Med. 2010 Jan;17(1):11-7. Article Link This evidence-based literature review of four prospective observational studies...
Red flags to screen for malignancy and fracture in patients with low back pain: systematic review
Journal Club Summary Methodology Score: 2.5/5 Usefulness Score: 2.5/5 Downie A, et al. BMJ 2013;347:f7095 Article Link This Cochrane review of the diagnostic accuracy of red flags for fracture or malignancy in patients with low back pain in multiple...
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial
Journal Club Summary Landmark Series Methodology Score: 4/5 Usefulness Score: 4/5 CRASH-2 trial collaborators Lancet. 2010 Jul 3;376(9734):23-32. Article Link This large RCT assessed the effect of early administration of tranexamic acid to trauma...
Reduction of adverse effects from intravenous acetylcysteine treatment for paracetamol poisoning: a randomised controlled trial
Journal Club Summary Methodology Score: 4/5 Usefulness Score: 2/5 Bateman DN, et al. Lancet. 2014 Feb 22;383(9918):697-704 Article Link This 2x2 factorial, intention to treat, randomized controlled trial of paracetamol overdose showed a modified...
