by Mark McKinney | Aug 11, 2022 | Commentary, COVID-19, Featured, Grand Round Summaries
The COVID-19 pandemic has been the most globally disruptive event of a generation. But is COVID a once in a lifetime event, or just another in a long line of infectious threats? Human history has been marked by new and re-emerging illnesses often on a global scale....
by Maria Doubova, Lucy Karp | Apr 28, 2022 | Cardiology, COVID-19, emergency, Featured, Grand Round Summaries
Chest pain is one of the most common presentations to the emergency department (ED) and includes a wide differential diagnosis. In today’s post, we will review a less common cause of chest pain seen in the ED: pericarditis and myocarditis. We will also review...
by Joyes Botros, Jeff Perry, Hans Rosenberg | Apr 18, 2022 | COVID-19, Full Article, Infectious Disease, Journal Club, landmark, Public health
Methodology: 4/5 Usefulness: 4/5 Gupta A, et al. N Engl J Med. 2021 Nov 18;385(21):1941-1950. Question and Methods: COMET-ICE trial evaluated the efficacy and safety of sotrovimab in high-risk, mild-to-moderate Covid-19 not requiring oxygen, within 5 days of symptom...
by Krishan Yadav | Jan 6, 2022 | Commentary, Featured, Journal Club
Sotrovimab Sotrovimab is a monoclonal antibody that neutralizes sarbecoviruses (respiratory viruses detected by PCR on oral/nasal swabs or from bronchial/lung/respiratory tract specimens). This antibody was first isolated from a patient with SARS-CoV-1 (the virus...
by Hans Rosenberg | Jul 26, 2021 | Full Article, Infectious Disease, Journal Club, landmark, Public health
Methodology: 4/5 Usefulness: 4.5/5 Polack FP, et al. N Engl J Med. 2020 Dec 31;383(27):2603-2615. doi: 10.1056/NEJMoa2034577. Epub 2020 Dec 10. Editorial: SARS-CoV-2 Vaccination – An Ounce (Actually, Much Less) of Prevention. Question/methods: Multinational,...