emottawa journal club Archives

Restrictive vs Liberal Transfusion Strategy in Patients With Acute Brain Injury: The TRAIN Randomized Clinical Trial

by Alie Wudwud, Hans Rosenberg, Christian Vaillancourt | Mar 24, 2025 | Featured, Journal Club, Neurosurgery, Trauma

Methodology: 3.5/5 Usefulness: 4/5 Taccone FS, et al. JAMA. 2024 Nov 19;332(19):1623-1633. Question and Methods: This multicenter, randomized trial aimed to determine the optimal hemoglobin transfusion threshold in patients with acute brain injury, comparing a...

Noninvasive Ventilation for Preoxygenation during Emergency Intubation

by Naman Arora, Hans Rosenberg, Christian Vaillancourt | Mar 10, 2025 | Airway, Anesthesiology, Critical Care, Full Article, Journal Club

Methodology: 4/5 Usefulness: 3.5/5 Gibbs KW, et al. N Engl J Med. 2024 Jun 20;390(23):2165-2177. Question and Methods: The PREOXI trial aimed to determine whether noninvasive ventilation (NIV) via BiPAP reduces hypoxemia compared to standard oxygen masks for...

Implementation of Electronic Health Record Integration and Clinical Decision Support to Improve Emergency Department Prescription Drug Monitoring Program Use

by Sangitha Mensingh, Hans Rosenberg, Krishan Yadav | Feb 6, 2025 | Featured, Journal Club, pharmacology

Methodology 3/5 Usefulness 2/5 Hoppe JA, et al. Ann Emerg Med. 2024 Jan;83(1):3-13. Question and Methods: The study evaluated whether integrating prescription drug monitoring program (PDMP) tools with clinical decision support in EHR workflows improved PDMP usage and...

Andexanet for Factor Xa Inhibitor-Associated Acute Intracerebral Hemorrhage

by Courtney Price, Hans Rosenberg, Krishan Yadav | Jan 27, 2025 | Full Article, Journal Club, Neurology, Neurosurgery, Thrombosis

Methodology 3/5 Usefulness 3/5 Connolly SJ, et al. N Engl J Med. 2024 May 16;390(19):1745-1755. Editorial: Reversing Oral Anticoagulation in Intracerebral Hemorrhage. Question and Methods: This unblinded, multicentre randomized controlled trial studied whether...

PECARN prediction rules for CT imaging of children presenting to the emergency department with blunt abdominal or minor head trauma: a multicentre prospective validation study

by Gabrielle Hibbert, Hans Rosenberg, Christian Vaillancourt | Jan 20, 2025 | Journal Club, Pediatric Care, Pediatrics, Trauma

Methodology: 3/5 Usefulness: 3/5 Holmes JF, et al. Lancet Child Adolesc Health. 2024 May;8(5):339-347. Question and Methods: This prospective multicenter cohort study sought to validate the PECARN intra-abdominal injury and traumatic brain injury rules in order to...