by Doran Drew | Jun 8, 2021 | Commentary, Critical Care, Grand Round Summaries, Journal Club, Resuscitation
Hey everyone! Buckle up. This is a long one. To provide context, I recently presented a 2-part blog post regarding thrombolytics in acute ischemic stroke. In these posts I explored the foundational literature for this tPA, as well as some of the common controversies I...
by Doran Drew, Josee Malette | May 27, 2021 | Featured, Grand Round Summaries, Neurology, Thrombosis
Addressing the Controversies Around Thrombolytic Therapy (tPA) In our previous blog post, we reviewed the formative literature supporting the currently used tPA time window. The figure below highlights a summary of the time windows investigated within each study and...
by Doran Drew, Josee Malette, Kate O'Connell | May 20, 2021 | Featured, Grand Round Summaries, Neurology, Thrombosis
Review of the formative literature of our current tPA time window in Acute Ischemic Stroke After numerous case series and smaller prospective studies suggesting benefit for thrombolytic therapy (tPA), the early 90s ushered in the era of thrombolytic RCTs for acute...
by Hashim Kareemi, Alie Wudwud | Apr 29, 2021 | Critical Care, Featured, Grand Round Summaries, Resuscitation
In Part 1 of our 2-series on Elevated ICP in the ED, Dr. Hashim Kareemi described the pathophysiology of elevated ICP and compared the options for diagnosis. Click here to review Part 1. In this Part 2 post, Dr. Kareemi takes us through a phased approach to managing...
by Hashim Kareemi, Alie Wudwud | Apr 22, 2021 | Critical Care, Featured, Grand Round Summaries, Resuscitation
This comprehensive, 2-part blog post by Dr. Hashim Kareemi reviews the current literature and guidelines on elevated ICP in the emergeny department. Part 1 reviews the pathophysiology and detrimental effects of sustained elevated ICP, and provides an excellent...