by Mathieu McKinnon, Jeff Perry, Shahbaz Syed | Mar 3, 2026 | Featured, Journal Club
Methodology: 4/5 Usefulness: 4/5 N Engl J Med. 2025 Dec 9. doi: 10.1056/NEJMoa2511420. Question and Methods: This multi-center, open label RCT of 2359 patients compared 28-day mortality in patients randomized to receiving ketamine or etomidate for their sedation prior...
by Nicholas Choi, Hans Rosenberg, Venkatesh Thiruganasambandamoorthy | Apr 28, 2025 | Airway, Critical Care, Full Article, Journal Club, Respirology
Methodology: 3/5 Usefulness: 3/5 Luo Z, et al. JAMA. 2024;332(20):1709–1722. doi:10.1001/jama.2024.15815 Question and Methods: Multi-centre, randomized control trial to determine whether a high-intensity NIPPV strategy reduces the need for intubation in AECOPD...
by Naman Arora, Hans Rosenberg, Christian Vaillancourt | Mar 10, 2025 | Airway, Anesthesiology, Critical Care, Full Article, Journal Club
Methodology: 4/5 Usefulness: 3.5/5 Gibbs KW, et al. N Engl J Med. 2024 Jun 20;390(23):2165-2177. Question and Methods: The PREOXI trial aimed to determine whether noninvasive ventilation (NIV) via BiPAP reduces hypoxemia compared to standard oxygen masks for...
by Nicholas Choi | Dec 5, 2024 | Anesthesiology, cardiac arrest, Grand Round Summaries, Respirology, Resuscitation
Quantitative End-Tidal CO2 (ETCO2) was in vogue for a while, and seemingly some centres adopted it as standard of care, while others found that it did not make a significant clinical impact so it fell out of style and left to ‘practitioner preference’....
by Min Joon Lee, Hans Rosenberg, Jeff Perry | Oct 28, 2024 | Airway, Anesthesiology, Critical Care, Journal Club, Pediatrics
Methodology: 4/5 Usefulness: 4/5 Geraghty LE, et al. N Engl J Med. 2024 May 30;390(20):1885-1894. doi: 10.1056/NEJMoa2402785. Question and Methods: Study aimed to determine if video laryngoscopy improves first-attempt intubation success in neonates compared to direct...
