Rapid Acute Coronary Syndrome Evaluation Over One Hour With High-Sensitivity Cardiac Troponin I: A United States-Based Stepped-Wedge, Randomized Trial

Rapid Acute Coronary Syndrome Evaluation Over One Hour With High-Sensitivity Cardiac Troponin I: A United States-Based Stepped-Wedge, Randomized Trial

by , , | Jul 14, 2025 | Cardiology, Full Article, Journal Club

Methodology: 4/5 Usefulness: 3.5/5 Miller J, et al. Ann Emerg Med. 2024 Oct;84(4):399-408. doi: 10.1016/j.annemergmed.2024.04.024.  Question and Methods: The Authors assessed whether a 0/1-hour high-sensitivity troponin protocol increased safe ED discharges compared...
Temporary mechanical circulatory support in infarct-related cardiogenic shock: an individual patient data meta-analysis of randomised trials with 6-month follow-up

Temporary mechanical circulatory support in infarct-related cardiogenic shock: an individual patient data meta-analysis of randomised trials with 6-month follow-up

by , , | Jun 17, 2025 | Cardiology, Critical Care, Journal Club

Methodology: 4/5 Usefulness: 1/5 Thiele H, et al. Lancet. 2024 Sep 14;404(10457):1019-1028. doi: 10.1016/S0140-6736(24)01448-X Question and Methods: Does routine early use of mechanical circulatory support (MCS) reduce mortality in acute myocardial infarction...
Test Characteristics of Emergency Medicine-Performed Point-of-Care Ultrasound for the Diagnosis of Acute Cholecystitis: A Systematic Review and Meta-analysis

Test Characteristics of Emergency Medicine-Performed Point-of-Care Ultrasound for the Diagnosis of Acute Cholecystitis: A Systematic Review and Meta-analysis

by , , | May 12, 2025 | Gastroenterology, Journal Club, Ultrasound

Methodology: 4/5 Usefulness: 3.5/5 Wilson SJ, et al. Ann Emerg Med. 2024 Mar;83(3):235-246. doi: 10.1016/j.annemergmed.2023.09.005. Questions and Method: To determine the diagnostic accuracy of emergency physician performed point of care ultrasound (POCUS) for acute...
Effect of High-Intensity vs Low-Intensity Noninvasive Positive Pressure Ventilation on the Need for Endotracheal Intubation in Patients With an Acute Exacerbation of Chronic Obstructive Pulmonary Disease: The HAPPEN Randomized Clinical Trial

Effect of High-Intensity vs Low-Intensity Noninvasive Positive Pressure Ventilation on the Need for Endotracheal Intubation in Patients With an Acute Exacerbation of Chronic Obstructive Pulmonary Disease: The HAPPEN Randomized Clinical Trial

by , , | Apr 28, 2025 | Airway, Critical Care, Full Article, Journal Club, Respirology

Methodology: 3/5 Usefulness: 3/5 Luo Z,  et al. JAMA. 2024;332(20):1709–1722. doi:10.1001/jama.2024.15815 Question and Methods: Multi-centre, randomized control trial to determine whether a high-intensity NIPPV strategy reduces the need for intubation in AECOPD...
Failure rate of D-dimer testing in patients with high clinical probability of pulmonary embolism: Ancillary analysis of three European studies

Failure rate of D-dimer testing in patients with high clinical probability of pulmonary embolism: Ancillary analysis of three European studies

by , , | Apr 7, 2025 | Featured, Full Article, Journal Club, Thrombosis

Methodology: 2.5/5 Usefulness: 2/5 Bannelier H, et al. Acad Emerg Med. 2025 Feb;32(2):116-122. doi: 10.1111/acem.15032.  Editorial: D-dimer in high-risk pulmonary embolism workup. Question and Methods: The authors performed a post-hoc analysis of three European...