by Emma Ferguson, Courtney Price | Jan 5, 2023 | Featured, Grand Round Summaries, Neurology
While most strokes we see are ischemic in nature, 10% of stroke presentations are intracerebral hemorrhages (ICH) 1. However, unlike ischemic strokes that have clear and evolving pathways for treatments, novel treatments for spontaneous intracerebral hemorrhages...
by Renee Bradley, Hans Rosenberg, Jeff Perry | May 2, 2022 | Critical Care, Journal Club, Neurology, Neurosurgery
Methodology: 4.5/5 Usefulness: 4/5 Post R, et al. Lancet. 2021 Jan 9;397(10269):112-118. doi: 10.1016/S0140-6736(20)32518-6. Question and Methods: This prospective, multicentre, randomized, controlled, open-label trial investigated whether administering TXA...
by Graham Wilson, Jeff Perry, Hans Rosenberg | Apr 4, 2022 | Full Article, Journal Club, Neurosurgery, Thrombosis, Trauma
Methodology: 3/5 Usefulness: 3/5 Grewal K, et al. CMAJ. 2021 Oct 12;193(40):E1561-E1567. Question and Methods: Retrospective cohort study evaluating risk of ICH post head injury in ED patients >65 years on warfarin or DOAC or no anticoagulant. Findings: Patients...
by Maeghan Fu, Josee Malette, Pascale King | Mar 11, 2021 | Grand Round Summaries, Hematology, Neurosurgery, Resuscitation, Trauma
Tick. Tock. It’s time for a TXA update. This blog post aims to arm you with the most up-to-date knowledge for the use of tranexamic acid (TXA) in the ED. We will review TXA in the context of gastrointestinal bleeding, traumatic brain injuries, hemoptysis,...
by Hans Rosenberg | Mar 18, 2019 | Critical Care, Full Article, Journal Club, landmark, Neurosurgery
Journal Club Methodology Score: 4/5 Usefulness Score: 3/5 Sprigg N, et al. Lancet. 2018 May 26;391(10135):2107-2115 Question and Methods: Multicenter, double-blinded, randomized, placebo-controlled trial comparing if IV TXA vs placebo, given within 8h of spontaneous...
