A non-inferiority randomized controlled trial of a shorter acetylcysteine regimen for paracetamol overdose – the SARPO trial

A non-inferiority randomized controlled trial of a shorter acetylcysteine regimen for paracetamol overdose – the SARPO trial

Methodology: 3.5/5 Usefulness: 4/5 Isbister G, et al. J Hepatol. 2025 Oct;83(4):881-887. doi: 10.1016/j.jhep.2025.05.008. Question and Methods: This multicentre unblinded RCT with 204 patients assessed non-inferiority of a 12-hour NAC protocol for single non-massive...
Test Characteristics of Emergency Medicine-Performed Point-of-Care Ultrasound for the Diagnosis of Acute Cholecystitis: A Systematic Review and Meta-analysis

Test Characteristics of Emergency Medicine-Performed Point-of-Care Ultrasound for the Diagnosis of Acute Cholecystitis: A Systematic Review and Meta-analysis

Methodology: 4/5 Usefulness: 3.5/5 Wilson SJ, et al. Ann Emerg Med. 2024 Mar;83(3):235-246. doi: 10.1016/j.annemergmed.2023.09.005. Questions and Method: To determine the diagnostic accuracy of emergency physician performed point of care ultrasound (POCUS) for acute...