by Hans Rosenberg | Jul 26, 2021 | Full Article, Infectious Disease, Journal Club, landmark, Public health
Methodology: 4/5 Usefulness: 4.5/5 Polack FP, et al. N Engl J Med. 2020 Dec 31;383(27):2603-2615. doi: 10.1056/NEJMoa2034577. Epub 2020 Dec 10. Editorial: SARS-CoV-2 Vaccination – An Ounce (Actually, Much Less) of Prevention. Question/methods: Multinational,...
by Hans Rosenberg | Jul 19, 2021 | Infectious Disease, Journal Club, Pediatrics
Methodology: 3/5 Usefulness: 1/5 Mas-Dalmau G, et al. Pediatrics. 2021 Mar;147(3):e20201323. doi: 10.1542/peds.2020-1323. Question and Methods: This RCT assessed effectiveness and safety of delayed (DAP), immediate (IAP) and no antibiotic prescription (NAP) in...
by Hans Rosenberg | Jun 14, 2021 | COVID-19, Infectious Disease, Journal Club, Respirology
Methodology: 2.5/5 Usefulness: 2/5 Ramakrishnan S, et al. Lancet Respir Med. 2021 Apr 9:S2213-2600(21)00160-0. Question and Methods: Is inhaled budesonide an effective treatment for patients with mild early symptoms of COVID-19? A randomized, open-label clinical trial...
by Hans Rosenberg | Jun 7, 2021 | Featured, Immunology, Infectious Disease, Journal Club
Methodology: 3/5 Usefulness: 2/5 Trubiano JA, et al. JAMA Intern Med. 2020 May 1;180(5):745-752. Question and Methods: Prospective derivation and subsequent retrospective validation of a clinical decision rule for the detection of patients at low risk for true...
by Hans Rosenberg | Apr 27, 2021 | COVID-19, Critical Care, Featured, Full Article, Infectious Disease, Journal Club
Methodology: 4/5 Usefulness: 4/5 WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group, Sterne JAC et al. JAMA. 2020 Oct 6;324(13):1330-1341. Question and Methods: Prospective meta-analysis of 7 RCTs investigating the utility of systemic...
by Hans Rosenberg | Dec 29, 2020 | Gastroenterology, Infectious Disease, Journal Club
Methodology: 2/5 Usefulness: 2/5 Jaung R, et al. Clin Gastroenterol Hepatol. 2020 Mar 30:S1542-3565(20)30426-2. Question and Methods: This study investigated non-inferiority of placebo vs antibiotic in management of uncomplicated diverticulitis by conducting an...
by Hans Rosenberg | Dec 7, 2020 | Critical Care, Featured, Infectious Disease, Journal Club
Methodology: 3.5/5 Usefulness: 3.5/5 Ann Intern Med. 2019 Oct 15;171(8):547-554. Cheng MP, et al. Question and Methods: Multi-center diagnostic study that investigated the sensitivity of post-antimicrobial blood cultures compared to pre-antimicrobial blood cultures in...
by Jessica McCallum, Alex Coutin | Oct 15, 2020 | Featured, Global health, Grand Round Summaries, Infectious Disease, Infectious Disease, Public health, Tropical Medicine
In part one of this two-part series, we took a bite out of Lyme disease and Malaria (see what we did there?). In this part, we’ll be covering African tick-bite fever, African sleeping sickness, Dengue, Chikungunya, and Zika. Fever in the returning traveler is...
by Jessica McCallum, Alex Coutin | Sep 24, 2020 | Featured, Global health, Grand Round Summaries, Infectious Disease, Public health, Tropical Medicine
In part one of a two-part series on vector-borne illnesses, we seek to take a deep dive into Lyme disease and Malaria. For more on the other vector-borne illnesses, check out part two! The only helpful way to distinguish between all these illnesses is the...
by Shahbaz Syed | Sep 17, 2020 | Featured, Infectious Disease
Here we present a STI ‘cheat sheet’ to commonly encountered STIs – their etiology, workup and treatment. The following recommendations are based on the Canadian PHAC guidelines. We will not cover the important aspect of taking a sexual history, but...
