by Amanda Mattice | Mar 25, 2026 | Anesthesiology, emergency, Journal Club, Pre-Hospital, Prehospital and Transport Medicine, PTM Journal Club, Trauma
In this month’s Journal Club, we explored the impact of post-intubation hypotension for critically ill trauma patients with severe traumatic brain injury (TBI) in the prehospital setting. Background and Study Objectives Trauma patients present with a variety of...
by Amanda Mattice | Mar 4, 2026 | Airway, emergency, Featured, Journal Club, Pre-Hospital, Prehospital and Transport Medicine, Procedural care, PTM Journal Club, Quality Improvement
In this month’s Journal Club, we explored the highly debated topic of video laryngoscopy versus direct laryngoscopy and its application in the prehospital setting. Background There exists a breadth of research which compares video laryngoscopy (VL) to direct...
by Mathieu McKinnon, Jeff Perry, Shahbaz Syed | Mar 3, 2026 | Featured, Journal Club
Methodology: 4/5 Usefulness: 4/5 N Engl J Med. 2025 Dec 9. doi: 10.1056/NEJMoa2511420. Question and Methods: This multi-center, open label RCT of 2359 patients compared 28-day mortality in patients randomized to receiving ketamine or etomidate for their sedation prior...
by Daniel Czikk, Hans Rosenberg, Venkatesh Thiruganasambandamoorthy | Dec 15, 2025 | Featured, Journal Club, Neurology
Methodology: 4/5 Usefulness: 4/5 Qiu Z, et al. N Engl J Med. 2025 Jul 10;393(2):139-150. doi: 10.1056/NEJMoa2503867. Question and Methods: This multi-center, open-label RCT of 550 patients in China with acute ischemic stroke due to large vessel occlusion presenting...
by Mohammed Ahmd, Amanda Mattice | Dec 11, 2025 | Journal Club, Prehospital and Transport Medicine
At this month’s Journal Club, we explored the use of IV vs IO access established during out-of-hospital cardiac arrests (OHCAs). In particular we took a deep dive into two trials: IVIO trial versus PARAMEDIC-3 trial Background Establishing vascular access...
by Amanda Mattice, Hans Rosenberg, Venkatesh Thiruganasambandamoorthy | Dec 8, 2025 | Journal Club, Urology
Methodology: 4/5 Usefulness: 3.5/5 Toumia M, et al. Ann Emerg Med. 2024 Dec;84(6):670-677. doi: 10.1016/j.annemergmed.2024.06.015. Question and Methods: This double-blinded RCT studied whether using adjuncts including MgSO4 and lidocaine are more effective than NSAID...
by Maria Berliant, Hans Rosenberg, Venkatesh Thiruganasambandamoorthy | Dec 1, 2025 | Full Article, Gastroenterology, Journal Club, Toxicology
Methodology: 3.5/5 Usefulness: 4/5 Isbister G, et al. J Hepatol. 2025 Oct;83(4):881-887. doi: 10.1016/j.jhep.2025.05.008. Question and Methods: This multicentre unblinded RCT with 204 patients assessed non-inferiority of a 12-hour NAC protocol for single non-massive...
by Faran Khalid, Hans Rosenberg, Ian Stiell | Nov 3, 2025 | Full Article, Journal Club, Neurology
Methodology: 3.5/5 Usefulness: 3.5/5 Alexandrov AW, et al. JAMA Neurol. 2025 Sep 1;82(9):905-914. doi: 10.1001/jamaneurol.2025.2253. Question and Methods: Authors aimed to determine if 0° head positioning reduces neurological deterioration and mortality in stroke...
by Kaitlin Endres, Hans Rosenberg, Ian Stiell | Oct 22, 2025 | Journal Club, Neurology
Methodology: 4.5/5 Usefulness: 4/5 Miao Z, et al. JAMA. 2025 Aug 19;334(7):582-591. doi: 10.1001/jama.2025.10800. Question and Methods: To compare clinical outcomes in patients with acute LVO for those who received intra-arterial tenecteplase after successful...
by Samara Adler, Hans Rosenberg, Krishan Yadav | Sep 29, 2025 | Gastroenterology, Journal Club, Pediatrics
Freedman SB, et al. N Engl J Med. 2025 Jul 17;393(3):255-266. doi: 10.1056/NEJMoa2503596. Methodology: 4.5/5 Usefulness: 4/5 Question and Methods: This multicentre, double-blind randomized superiority trial evaluated the effectiveness of oral ondansetron dispensed at...
