External validation of a low HEAR score to identify emergency department chest pain patients at very low risk of major adverse cardiac events without troponin testing

External validation of a low HEAR score to identify emergency department chest pain patients at very low risk of major adverse cardiac events without troponin testing

by , , | Feb 28, 2022 | Cardiology, Featured, Journal Club

Methodology: 3.5/5 Usefulness: 2.5/5 O’Rielly CM, et al. CJEM. 2021 Jul 17. doi: 10.1007/s43678-021-00159-y. Question and Methods:  Secondary analysis validation study that sought to validate proposed HEAR score’ ability to identify low risk patients for acute...
Self-obtained vaginal swabs are not inferior to provider-performed endocervical sampling for emergency department diagnosis of Neisseria gonorrhoeae and Chlamydia trachomatis

Self-obtained vaginal swabs are not inferior to provider-performed endocervical sampling for emergency department diagnosis of Neisseria gonorrhoeae and Chlamydia trachomatis

by , , | Feb 7, 2022 | Infectious Disease, Journal Club, OBGYN

Methodology: 3/5 Usefulness:2/5 Chinnock B, et al. Acad Emerg Med. 2021 Jun;28(6):612-620. doi: 10.1111/acem.14213.  Question and Methods:  This prospective observational cohort trial sought to assess if self-obtained vaginal swabs were not inferior to...
Direct-access physiotherapy to help manage patients with musculoskeletal disorders in an emergency department: Results of a randomized controlled trial

Direct-access physiotherapy to help manage patients with musculoskeletal disorders in an emergency department: Results of a randomized controlled trial

by , , | Jan 31, 2022 | Journal Club, Orthopedics

Methodology: 2/5 Usefulness: 2.5/5 Gagnon R, et al. Acad Emerg Med. 2021 Aug;28(8):848-858. doi: 10.1111/acem.14237. Question and Methods: RCT to assess if direct access to Physiotherapy (PT) in the ED could reduce pain interference on function, pain intensity as well...
Effect of 12 mg vs 6 mg of Dexamethasone on the Number of Days Alive Without Life Support in Adults With COVID-19 and Severe Hypoxemia: The COVID STEROID 2 Randomized Trial

Effect of 12 mg vs 6 mg of Dexamethasone on the Number of Days Alive Without Life Support in Adults With COVID-19 and Severe Hypoxemia: The COVID STEROID 2 Randomized Trial

by , , | Jan 24, 2022 | Full Article, Infectious Disease, Journal Club

Methodology: 3.5/5 Usefulness: 3.5/5 COVID STEROID 2 Trial Group, Munch MW, et al. JAMA. 2021 Nov 9;326(18):1807-1817. doi: 10.1001/jama.2021.18295. Question and Methods: This blinded randomized clinical trial compared the effects of 12 mg daily relative to 6 mg daily...
A randomized double-blind trial comparing the effect on pain of an oral sucrose solution versus placebo in children 1-3 months old needing bladder catheterization

A randomized double-blind trial comparing the effect on pain of an oral sucrose solution versus placebo in children 1-3 months old needing bladder catheterization

by , | Jan 10, 2022 | Featured, Full Article, Journal Club, Pediatrics

Methodology: 4/5 Usefulness: 2/5 Desjardins MP, et al. CJEM. 2021 Sep;23(5):655-662. doi: 10.1007/s43678-021-00130-x. Epub 2021 May 26. Question and Methods: This double-blinded RCT compares analgesic efficacy of oral sucrose versus placebo in bladder catheterization...
COMET-ICE Trial on Sotrovimab

COMET-ICE Trial on Sotrovimab

by | Jan 6, 2022 | Commentary, Featured, Journal Club

Sotrovimab Sotrovimab is a monoclonal antibody that neutralizes sarbecoviruses (respiratory viruses detected by PCR on oral/nasal swabs or from bronchial/lung/respiratory tract specimens). This antibody was first isolated from a patient with SARS-CoV-1 (the virus...