We are excited to introduce the Sixth edition of The Ottawa Handbook of Emergency Medicine. Your bedside guide for approaches to various Emergency Medicine presentations.
Highlights of the Sixth edition include the addition of: Oncologic emergencies, approach to the pregnant patient, geriatrics and more!
Efficacy and safety of recombinant activated factor VII for acute intracerebral hemorrhage.
Journal Club Summary Landmark Series Mayer SA, Brun NC, Begtrup K, Broderick J, Davis S, Diringer MN, et al. N Engl J Med. 2008 May 15;358(20):21 27–37. Article Link This industry sponsored, international multicentre RCT involved 841 patients with acute ICH and found...
Hydrocortisone therapy for patients with septic shock.
Journal Club Summary Landmark Series Sprung CL, Annane D, Keh D, Moreno R, Singer M, Freivogel K, et al. N Engl J Med. 2008 Jan.10;358(2):111–24. Article Link This European multicentre RCT compared hydrocortisone to placebo for 499 ICU patients with septic shock and...
Does this adult patient have septic arthritis?
Journal Club Summary Landmark Series Margaretten ME, Kohlwes J, Moore D, Bent S. JAMA. 2007Apr.4;297(13):1478–88. Article Link This systematic overview from the excellent JAMA series reviewed the relatively weak evidence regarding assessment of patients with...
Randomized, Controlled Trial of Acetaminophen, Ibuprofen, and Codeine for Acute Pain Relief in Children With Musculoskeletal Trauma.
Journal Club Summary Landmark Series Clark E, Plint AC, Correll R, Gaboury I, Passi B. A Pediatrics. 20 07Mar.1;119(3):460–7. Article Link This high quality RCT by local investigators rigorously compared acetaminophen, ibuprofen and codeine analgesics among...
How do I perform a lumbar puncture and analyze the results to diagnose bacterial meningitis?
Journal Club Summary Landmark Series Straus SE, Thorpe KE, Holroyd-Leduc J. JAMA. 2006Oct.25;296(16):2012–22. PubMed Link This systematic literature review and meta-analysis in the Rational Clinical Examination series found a non-significant trend towards less...
Safety and Efficacy of Hydromorphone as an Analgesic Alternative to Morphine in Acute Pain: A Randomized Clinical Trial
Journal Club Summary Landmark Series Andrew K Chang, Polly E Bijur, Robert H Meyer, Mark K Kenny, Clemencia Solorzano, and E John Gallagher PubMed Link This U.S. randomized trial in ED adults with severe pain found similar effectiveness for intravenous...
Laryngeal View During Laryngoscopy: A Randomized Trial Comparing Cricoid Pressure, Backward-Upward-Rightward Pressure, and Bimanual Laryngoscopy
Journal Club Summary Landmark Series Levitan RM, Kinkle WC, Levin WJ, Everett WW. Ann Emerg Med. 2006 Jun.;47(6):548–55. PubMed Link This U.S. study evaluated manipulation techniques for direct laryngoscopy during endotracheal intubation in 1,530 comparisons performed...
Early versus Later Rhythm Analysis in Patients with Out-of-Hospital Cardiac Arrest
Journal Club Summary Methodology: 4.5/5 Usefulness: 4/5 Stiell IG, Nichol G, Leroux BG, Rea TD, Ornato JP, Powell J, Christenson J, Callaway CW, Kudenchuk PJ, Aufderheide TP, Idris AH, Daya MR, Wang HE, Morrison LJ, Davis D, Andrusiek D, Stephens S, Cheskes S,...
International collaborative systematic review of controlled clinical trials on pharmacologic treatments for acute pericarditis and its recurrences
Journal Club Summary Methodology: 2/5 Usefulness: 3/5 Lotrionte M, Biondi-Zoccai G, Imazio M, Castagno D, Moretti C, Abbate A, Agostoni P, Brucato AL, Di Pasquale P, Raatikka M, Sangiorgi G, Laudito A, Sheiban I, Gaita F. Am Heart J. 2010 Oct;160(4):662-70....
Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials
Journal Club Summary Methodology: 4/5 Usefulness: 4.5/5 Lees KR, Bluhmki E, von Kummer R, Brott TG, Toni D, Grotta JC, Albers GW, Kaste M, Marler JR, Hamilton SA, Tilley BC, Davis SM, Donnan GA, Hacke W; ECASS, ATLANTIS, NINDS and EPITHET rt-PA Study Group, Allen...
