Phenobarbital treatment of alcohol withdrawal in the emergency department: A systematic review and meta-analysis
Methodology: 4/5 Usefulness: 2/5 Lee CM, et al. Acad Emerg Med. 2024 May;31(5):515-524. Question and Methods: This is a systematic review and meta-analysis comparing... Read more.
Temporary mechanical circulatory support in infarct-related cardiogenic shock: an individual patient data meta-analysis of randomised trials with 6-month follow-up
Methodology: 4/5 Usefulness: 1/5 Thiele H, et al. Lancet. 2024 Sep 14;404(10457):1019-1028. doi: 10.1016/S0140-6736(24)01448-X Question and Methods: Does routine... Read more.
High-Flow Nasal Oxygen vs Noninvasive Ventilation in Patients With Acute Respiratory Failure: The RENOVATE Randomized Clinical Trial
Methodology: 3.5/5 Usefulness: 3/5 RENOVATE Investigators and the BRICNet Authors; et al. JAMA. 2025 Mar 11;333(10):875-890. doi: 10.1001/jama.2024.26244. Question... Read more.
Diagnostic Accuracy of D-Dimer for Acute Aortic Syndromes: Systematic Review and Meta-Analysis
Methodology: 3/5 Usefulness: 4/5 Essat M, et al. Ann Emerg Med. 2024 Jun 18:S0196-0644(24)00260-9 Question and Methods: Using systematic review methodology, the... Read more.
Test characteristics of point-of-care ultrasonography in patients with acute kidney injury.
Methodology: 2.5/5 Usefulness: 3.5/5d Gaudreau-Simard M, et al. Ultrasound J. 2024 Feb 22;16(1):15. doi: 10.1186/s13089-023-00352-3. Question and Methods: The authors... Read more.
Comparing the efficacy of intravenous morphine versus ibuprofen or the combination of ibuprofen and acetaminophen in patients with closed limb fractures: a randomized clinical trial
Methodology: 3.5/5 Usefulness: 2/5 Nasr Isfahani M, et al. BMC Emerg Med. 2024 Jan 25;24(1):15. Question and Methods: This triple blinded RCT of 158 patients with... Read more.
Ketamine Compared With Morphine for Out-of-Hospital Analgesia for Patients With Traumatic Pain: A Randomized Clinical Trial
Methodology: 3/5 Usefulness: 1.5/5 Le Cornec C, e al. JAMA Netw Open. 2024 Jan 2;7(1):e2352844. Question and Methods: This was a multicenter, single-blind, noninferiority... Read more.
Short Oral Antibiotic Therapy for Pediatric Febrile Urinary Tract Infections: A Randomized Trial
Methodology: 3.5/5 Usefulness: 2.5/5 Montini G, et al. Pediatrics. 2024 Jan 1;153(1):e2023062598. Question and Methods: This multicenter, parallel-group randomized... Read more.
Early Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension
Methodology: 4/5 Usefulness: 3/5 National Heart, Lung, and Blood Institute Prevention and Early Treatment of Acute Lung Injury Clinical Trials Network; et al. N... Read more.
Early Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest
Methodology: 4/5 Usefulness: 2.5/5 Suverein MM, et al. N Engl J Med. 2023 Jan 26;388(4):299-309. doi: 10.1056/NEJMoa2204511. Question and Methods: Does eCPR increase... Read more.