by Maria Berliant, Hans Rosenberg, Venkatesh Thiruganasambandamoorthy | Dec 1, 2025 | Full Article, Gastroenterology, Journal Club, Toxicology
Methodology: 3.5/5 Usefulness: 4/5 Isbister G, et al. J Hepatol. 2025 Oct;83(4):881-887. doi: 10.1016/j.jhep.2025.05.008. Question and Methods: This multicentre unblinded RCT with 204 patients assessed non-inferiority of a 12-hour NAC protocol for single non-massive...
by Shahbaz Syed | Nov 14, 2024 | Commentary, Featured, Toxicology
Urine drug (or toxicologic) screens are a fairly standard tool used in addictions, psychiatry and the Emergency Department (ED), often employed to detect substance use in patients presenting with altered mental status, trauma, psychiatric or abnormal behaviour. Yet,...
by Kaitlin Endres | Nov 7, 2024 | Airway, Anesthesiology, cardiac arrest, Featured, Grand Round Summaries, Infectious Disease, Radiology, Respirology, Toxicology
Inhalational injuries are a critical yet often overlooked aspect of trauma care, with far-reaching consequences in emergency medicine. These injuries can arise from various sources, including thermal injuries from fires, recreational activities such as smoke exposure...
by Rebecca Seliga | Oct 17, 2024 | Critical Care, Featured, Grand Round Summaries, pharmacology, Resuscitation, Toxicology
We remain amid an opioid crisis in Canada, with over 8000 deaths (or 22/day) in 2023. The harms of opioid use in society are devastating and cannot be understated – but so too are the harms from stimulant and other substance use. In 2023 there were 3479 apparent...
by Jessica Tat | Jul 4, 2024 | Featured, Grand Round Summaries, Toxicology
We all know medications can help us feel better and stay healthy but as we are all familiar, sometimes drug interactions can be overlooked and cause significant adverse health outcomes. Drug interactions are common clinical problems that can occur in several different...
by Camille Dagenais | May 23, 2024 | Addictions, cardiac arrest, Chronic Pain, Featured, Toxicology
The North American opioid crisis is rapidly expanding, resulting in unprecedented levels of harm and strain on the healthcare system. The opioid epidemic is not new to ED providers across the country, but the true extent of harm is quite shocking. In Canada, there has...
by Dr. Stephanie Lim-Reinders, Stephanie Davenport | May 2, 2024 | cheo, Commentary, Critical Care, Featured, Grand Round Summaries, Pediatrics, Toxicology
In the pursuit of holistic health and wellness, individuals often turn to naturopathy as a beacon of alternative medicine, seeking relief and healing outside the realm of conventional treatments. Yet, amidst the allure of natural remedies and lifestyle adjustments,...
by Amanda Mattice | Mar 7, 2024 | emergency, Featured, Grand Round Summaries, Pre-Hospital, Prehospital and Transport Medicine, Resuscitation, Toxicology
In this post, we will sink our teeth into some details around venomous snake bites that all emergency clinicians should be aware of regardless of their location of clinical practice. Although the incidence of venomous snake bites in Canada is rare, this should be...
by Brenton Wong, Hans Rosenberg, Krishan Yadav | Feb 26, 2024 | Airway, Critical Care, Featured, Journal Club, Toxicology
Methodology: 3.5/5 Usefulness: 3/5 Freund Y, et al. JAMA. 2023 Dec 19;330(23):2267-2274. Question and Methods: Multicenter RCT involving comatose patients with suspected acute poisoning and GCS <9 compared a conservative airway strategy of withholding intubation...
by Steven Sanders | Jul 6, 2023 | Critical Care, Featured, Grand Round Summaries, Pre-Hospital, Resuscitation, Toxicology
Global temperatures are increasing and are projected to continue warming. The rates of warming across out planet are not uniform. In Canada, the loss of snow and sea ice reduces the reflectivity of the surface leading to increased absorption of solar radiation and a...
