The twitter Pandemic: the critical role of information dissemination
Originally published in CJEM 2020, we explore the role of twitter in the dissemination of medical information/misinformation during the COVID-19 pandemic. Read the... Read more.
Oseltamivir plus usual care versus usual care for influenza-like illness in primary care: an open-label, pragmatic, randomised controlled trial.
Methodology: 3/5 Usefulness: 3/5 Butler CC, et al. Lancet. 2020 Jan 4;395(10217):42-52. Editorial: Neuraminidase inhibitors for influenza-like illness in primary... Read more.
Conservative versus Interventional Treatment for Spontaneous Pneumothorax
Methodology: 2/5 Usefulness: 3/5 Brown SGA, et al. N Engl J Med. 2020 Jan 30;382(5):405-415. Question and Methods: Is conservative/observational treatment of moderate-large... Read more.
C-Reactive Protein Testing to Guide Antibiotic Prescribing for COPD Exacerbations.
Methodology: 3/5 Usefulness: 2.5/5 Butler CC, et al. N Engl J Med. 2019 Jul 11;381(2):111-120 Editorial: COPD Exacerbations – A Target for Antibiotic Stewardship.... Read more.
Ticagrelor or Prasugrel in Patients with Acute Coronary Syndromes
Methodology Score: 4/5 Usefulness Score: 4/5 Schüpke S, et al N Engl J Med. 2019 Oct 17;381(16):1524-1534. Editorial: Ticagrelor or Prasugrel in Acute Coronary... Read more.
Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial
Methodology: 4/5 Usefulness: 3/5 Fujii T, et al. JAMA. 2020 Jan 17. doi: 10.1001/jama.2019.22176. Editorial: Lack of Benefit of High-Dose Vitamin C, Thiamine, and... Read more.
Alcohol Abstinence in Drinkers with Atrial Fibrillation
Methodology: 5/5 Usefulness: 3.5/5 Voskoboinik A, et al. N Engl J Med. 2020 Jan 2;382(1):20-28. Editorial: A Sober Reality? Alcohol, Abstinence, and Atrial Fibrillation.... Read more.
Randomized Trial of Three Anticonvulsant Medications for Status Epilepticus
Methodology Score: 4/5 Usefulness Score: 3.5/5 Kapur J et al. N Engl J Med. 2019 Nov 28;381(22):2103-2113. Question and Methods: A multicenter, randomized, blinded,... Read more.
Subdissociative‐dose Ketamine Is Effective for Treating Acute Exacerbations of Chronic Pain
Methodology: 2/5 Usefulness: 2.5 /5 Lumanauw DD, et al. Acad Emerg Med. 2019 Sep;26(9):1044-1051. doi: 10.1111/acem.13755. Epub 2019 Apr 29. Question and Methods:... Read more.
Oral Lefamulin vs Moxifloxacin for Early Clinical Response Among Adults With Community-Acquired Bacterial Pneumonia: The LEAP 2 Randomized Clinical Trial
Methodology: 4/5 Usefulness: 2/5 Alexander E., et al. JAMA. 2019 Sep 27. doi: 10.1001/jama.2019.15468. Editorial: Lefamulin-A New Antibiotic for Community-Acquired Pneumonia.... Read more.