by Hans Rosenberg | May 10, 2021 | ENT, Featured, Journal Club, Thrombosis
Methodology: 3/5 Usefulness: 3/5 Reuben A, et al. Ann Emerg Med. 2021 Feb 18:S0196-0644(20)31461-X. Question and Methods: This was a double-blind, randomized controlled trial comparing topical tranexamic acid to placebo in patients presenting to the ED with epistaxis...
by Jim Yang, Kaitlin Endres, Josee Malette | Nov 19, 2020 | Critical Care, Featured, Grand Round Summaries, Medical Education, Thrombosis
Pulmonary embolism is often a nebulous diagnosis with various nuances. COMMON: They affect 25-100 people per 100,000, or approximately 30,000 Canadians every year Potentially FATAL: 3rd most deadly cardiovascular disease, after Heart Attack and Stroke Associated with...
by Hans Rosenberg | Nov 16, 2020 | Critical Care, Journal Club, Resuscitation, Thrombosis, Trauma
Methodology: 4/5 Usefulness: 3.5/5 Baksaas-Aasen K, et al. Intensive Care Med. 2020 Oct 13. doi: 10.1007/s00134-020-06266-1. Question and Methods: Pragmatic, European, multi-center RCT comparing outcomes in trauma patients who received empiric massive transfusion...
by Hans Rosenberg | Mar 23, 2020 | Cardiology, Featured, Journal Club, Thrombosis
Methodology Score: 4/5 Usefulness Score: 4/5 Schüpke S, et al N Engl J Med. 2019 Oct 17;381(16):1524-1534. Editorial: Ticagrelor or Prasugrel in Acute Coronary Syndromes – The Winner Takes It All? Question and Methods: This open-label multicenter trial was the...
by Hans Rosenberg | Feb 10, 2020 | Journal Club, landmark, Thrombosis
Methodology Score: 4/5 Usefulness Score: 4.5/5 Kearon C, et al. N Engl J Med. 2019 Nov 28;381(22):2125-2134 Question and Methods: the authors sought to demonstrate safety using a d-dimer cut-off of 1000ng/mL for low pre-test probability patients & a cut-off of...
by Hans Rosenberg | Aug 19, 2019 | Journal Club, OBGYN, Thrombosis
Journal Club Summary Methodology Score: 4.5/5 Usefulness Score: 4.5 /5 van der Pol LM, et al. N Engl J Med. 2019 Mar 21;380(12):1139-1149 Question and Methods: Using a prospective cohort study of 510 pregnant women, the authors were trying to see whether an algorithm...
by Hans Rosenberg | May 13, 2019 | Journal Club, Thrombosis
Journal Club Summary Methodology: 2.5/5 Usefulness: 2/5 Connolly SJ, et al. N Engl J Med. 2019 Feb 7. Question and Methods: This was the first trial looking at clinical outcomes for reversal of factor Xa inhibitor anticoagulation in major bleeding episodes using the...
by Hans Rosenberg | Dec 17, 2018 | Featured, Journal Club, Thrombosis
Journal Club Summary Methodology: 4/5 Usefulness: 4/5 Kent AP, et al. J Am Coll Cardiol. 2018 Jul 17;72(3):255-267 Question and Methods: This was a post hoc analysis of the RE-LY trial examining the risk of NSAID use in patients receiving oral anticoagulation (OAC)...
by Robert Suttie, Matthew Lipinski | Feb 15, 2018 | cardiac arrest, Cardiology, Critical Care, Resuscitation, Thrombosis
There are a few specific arrhythmias that we encounter often in the ED that deserve a little bit more thought. Dr. Matthew Lipinski takes us through a few updates in the area beyond the routine basics. For other Grand Rounds Summaries please see our archives. Chronic...
by Hans Rosenberg | Oct 23, 2017 | Journal Club, landmark, Thrombosis
Journal Club Summary Reference: Van der Hulle T, et al. Lancet. 2017 Jul 15;390(10091):289-297. Methodology Score: 4/5 Usefulness Score: 3.5/5 Questions and Methods: This multicenter trial implemented the YEARS simplified algorithm for suspected PE...
