
Implementation of a standardized pregnancy screening process to address gender disparities in radiology turn-around-time and ED length of stay
Methodology: 1.5/5 Usefulness: 1.5/5 Loke DE, et al. CJEM. 2022 Mar;24(2):206-213. Question and Methods: Trying to quantify gender disparities in CT turnaround time... Read more.

Efficacy and Safety of Early Administration of 4-Factor Prothrombin Complex Concentrate in Patients With Trauma at Risk of Massive Transfusion: The PROCOAG Randomized Clinical Trial
Methodology: 4/5 Usefulness: 3.5/5 Bouzat P, et al. JAMA. 2023 Mar 21:e234080. doi: 10.1001/jama.2023.4080. Question and Methods: This double-blind, randomized,... Read more.

Quality initiative to improve emergency department sepsis bundle compliance through utilisation of an electronic health record tool
Methodology: 2/5 Usefulness: 3/5 Warstadt NM, et al. BMJ Open Qual. 2022 Jan;11(1):e001624. Questions and Methods: Using a cohort and QI approach, to demonstrate... Read more.

Safely reducing abdominal/pelvic computed tomography imaging in pediatric trauma: a quality improvement initiative
Methodology: 4.5/5 Usefulness: 5/5 Beno S, al. CJEM. 2022 Aug;24(5):535-543. Editorial: Reducing overuse of CT imaging in pediatric trauma: a model example of... Read more.

Acetazolamide in Acute Decompensated Heart Failure with Volume Overload
Methodology Score: 4/5 Usefulness Score: 2/5 (Emergency) 4/5 (Internal medicine) Mullens W, et al. N Engl J Med.... Read more.

Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest
Methodology: 4/5 Usefulness: 4/5 Kjaergaard J, et al. N Engl J Med. 2022 Oct 20;387(16):1456-1466. Question and Methods: This was a double-blind, randomized trial... Read more.

RAFF-3 Trial: A Stepped-Wedge Cluster Randomised Trial to Improve Care of Acute Atrial Fibrillation and Flutter in the Emergency Department
Methodology: 4/5 Usefulness: 5/5 Stiell IG, et al. Can J Cardiol. 2021 Oct;37(10):1569-1577. Question and Methods: Using a stepped wedge cluster randomized trial,... Read more.

Thrombectomy for anterior circulation stroke beyond 6 h from time last known well (AURORA): a systematic review and individual patient data meta-analysis
Methodology: 3/5 Usefulness: 2/5 Jovin TG, et al. Lancet. 2022 Jan 15;399(10321):249-258. doi: 10.1016/S0140-6736(21)01341-6. Editorial: Late thrombectomy for ischaemic... Read more.

Ultra-early tranexamic acid after subarachnoid haemorrhage (ULTRA): a randomised controlled trial
Methodology: 4.5/5 Usefulness: 4/5 Post R, et al. Lancet. 2021 Jan 9;397(10269):112-118. doi: 10.1016/S0140-6736(20)32518-6. Question and Methods: This prospective,... Read more.

Early Treatment for Covid-19 with SARS-CoV-2 Neutralizing Antibody Sotrovimab
Methodology: 4/5 Usefulness: 4/5 Gupta A, et al. N Engl J Med. 2021 Nov 18;385(21):1941-1950. Question and Methods: COMET-ICE trial evaluated the efficacy and safety... Read more.