Thrombectomy for anterior circulation stroke beyond 6 h from time last known well (AURORA): a systematic review and individual patient data meta-analysis
Methodology: 3/5 Usefulness: 2/5 Jovin TG, et al. Lancet. 2022 Jan 15;399(10321):249-258. doi: 10.1016/S0140-6736(21)01341-6. Editorial: Late thrombectomy for ischaemic... Read more.
Ultra-early tranexamic acid after subarachnoid haemorrhage (ULTRA): a randomised controlled trial
Methodology: 4.5/5 Usefulness: 4/5 Post R, et al. Lancet. 2021 Jan 9;397(10269):112-118. doi: 10.1016/S0140-6736(20)32518-6. Question and Methods: This prospective,... Read more.
A Prospective Evaluation of Clinical HEART Score Agreement, Accuracy, and Adherence in Emergency Department Chest Pain Patients
Methodology: 3/5 Usefulness: 2/5 Soares WE 3rd, et al. Ann Emerg Med. 2021 Aug;78(2):231-241. Questions and Methods: This study compared agreement in HEART scores... Read more.
Early Treatment for Covid-19 with SARS-CoV-2 Neutralizing Antibody Sotrovimab
Methodology: 4/5 Usefulness: 4/5 Gupta A, et al. N Engl J Med. 2021 Nov 18;385(21):1941-1950. Question and Methods: COMET-ICE trial evaluated the efficacy and safety... Read more.
Intracranial hemorrhage after head injury among older patients on anticoagulation seen in the emergency department: a population-based cohort study
Methodology: 3/5 Usefulness: 3/5 Grewal K, et al. CMAJ. 2021 Oct 12;193(40):E1561-E1567. Question and Methods: Retrospective cohort study evaluating risk of ICH... Read more.
Effect of Use of a Bougie vs Endotracheal Tube With Stylet on Successful Intubation on the First Attempt Among Critically Ill Patients Undergoing Tracheal Intubation: A Randomized Clinical Trial
Methodology: 4/5 Usefulness: 3/5 Driver BE, et al. JAMA. 2021 Dec 28;326(24):2488-2497. Question and Methods: Multicentre unblinded pragmatic trial comparing... Read more.
Artificial Intelligence to Detect Papilledema from Ocular Fundus Photographs
Methodology: 4/5 Usefulness: 3/5 Milea D, et al. N Engl J Med. 2020 Apr 30;382(18):1687-1695. Question and Methods: The authors developed a deep learning system... Read more.
External validation of a low HEAR score to identify emergency department chest pain patients at very low risk of major adverse cardiac events without troponin testing
Methodology: 3.5/5 Usefulness: 2.5/5 O’Rielly CM, et al. CJEM. 2021 Jul 17. doi: 10.1007/s43678-021-00159-y. Question and Methods: Secondary analysis validation... Read more.
Self-obtained vaginal swabs are not inferior to provider-performed endocervical sampling for emergency department diagnosis of Neisseria gonorrhoeae and Chlamydia trachomatis
Methodology: 3/5 Usefulness:2/5 Chinnock B, et al. Acad Emerg Med. 2021 Jun;28(6):612-620. doi: 10.1111/acem.14213. Question and Methods: This prospective observational... Read more.
Direct-access physiotherapy to help manage patients with musculoskeletal disorders in an emergency department: Results of a randomized controlled trial
Methodology: 2/5 Usefulness: 2.5/5 Gagnon R, et al. Acad Emerg Med. 2021 Aug;28(8):848-858. doi: 10.1111/acem.14237. Question and Methods: RCT to assess if direct... Read more.