Effect of Abdominal Ultrasound on Clinical Care, Outcomes, and Resource Use Among Children With Blunt Torso Trauma: A Randomized Controlled Trial

Journal Club Summary Reference: Holmes JF, et al. JAMA. 2017 Jun 13;317(22):2290-2296 Editorial: Abdominal Ultrasound for Pediatric Blunt Trauma: FAST Is Not Always Better. Reference: Kessler DO. JAMA. 2017 Jun 13;317(22):2283-2285. Methodology Score: 4/5 Usefulness Score: 3.5/5 Question and Methods: Single center, unblinded, RCT assessed the use of FAST examination in the evaluation of stable blunt torso trauma in the pediatric population. Findings: The use […]

Simplified diagnostic management of suspected pulmonary embolism (the YEARS study): a prospective, multicentre, cohort study

Journal Club Summary Reference: Van der Hulle T, et al. Lancet. 2017 Jul 15;390(10091):289-297.  Methodology Score: 4/5                   Usefulness Score: 3.5/5 Questions and Methods: This multicenter trial implemented the YEARS simplified algorithm for suspected PE at 12 Netherlands sites in over 3000 patients. Findings: The algorithm was safe (0.61% had VTE), and effective at reducing CTPA by 14% when compared to […]

Ibuprofen versus fosfomycin for uncomplicated urinary tract infection in women: randomised controlled trial

Journal Club Summary Reference: Gágyor I, et al. BMJ. 2015 Dec 23;351:h6544 Methodology Score: 4/5 Usefulness Score: 2.5/5 This multicenter, double blinded, randomized controlled trial assessed the use of ibuprofen versus fosfomycin in uncomplicated UTIs in women aged 18-65. The study assessed antibiotic usage, symptom burden, and complications arising from UTIs. While those patients randomized to ibuprofen had significantly fewer […]

Association Between Early Participation in Physical Activity Following Acute Concussion and Persistent Postconcussive Symptoms in Children and Adolescents

Journal Club Summary Methodology Score: 3.5/5 Usefulness Score: 3/5 Grool AM, et al. JAMA. 2016 Dec 20;316(23):2504-2514. EDITORIAL: Physical Activity or Rest After Concussion in Youth: Questions About Timing and Potential Benefit. Chrisman SP JAMA. 2016 Dec 20;316(23):2491-2492. doi: 10.1001/jama.2016.17562. This prospective multicenter cohort study found a possible relation between early physical activity (<7 days) and a lower PPCS at 28 days […]

Time to Treatment and Mortality during Mandated Emergency Care for Sepsis

Journal Club Summary Seymour CW, et al. Journal N Engl J Med. 2017 Jun 8;376(23):2235-2244. EDITORIAL: State Sepsis Mandates – A New Era for Regulation of Hospital Quality. Hershey TB, et al. N Engl J Med. 2017 May 21. Methodology Score:  3.5/5 Usefulness Score:  3/5 This large retrospective review of observational data from 185 hospitals (49,331 patients) with severe sepsis or […]