A randomized double-blind trial comparing the effect on pain of an oral sucrose solution versus placebo in children 1-3 months old needing bladder catheterization
Methodology: 4/5 Usefulness: 2/5 Desjardins MP, et al. CJEM. 2021 Sep;23(5):655-662. doi: 10.1007/s43678-021-00130-x. Epub 2021 May 26. Question and Methods: This... Read more.
Rapid Agitation Control With Ketamine in the Emergency Department: A Blinded, Randomized Controlled Trial
Methodology: 3.5/5 Usefulness: 3.5/5 Barbic D, et al. Ann Emerg Med. 2021 Aug 2:S0196-0644(21)00433-9. Question and Methods: Randomized, single center, blinded clinical... Read more.
Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest
Methodology: 5/5 Usefulness: 5/5 Dankiewicz J, et al. N Engl J Med. 2021 Jun 17;384(24):2283-2294. Question and Methods: Open-label multicentre randomized controlled... Read more.
Milrinone as Compared with Dobutamine in the Treatment of Cardiogenic Shock
Methodology: 3.5/5 Usefulness: 3.5/5 Mathew R, et al. N Engl J Med. 2021 Aug 5;385(6):516-525. Question and Methods: The authors performed a double-blinded RCT... Read more.
Efficacy of ketamine for initial control of acute agitation in the emergency department: A randomized study
Methodology: 2.5/5 Usefulness: 3/5 Lin J, et al. Am J Emerg Med. 2021 Jun;44:306-311. Question and Methods: Open-label prospective study comparing the efficacy and... Read more.
Prospective, Multicenter, Controlled Trial of Mobile Stroke Units
Methodology: 2.5 5 Usefulness: 2.5/5 Grotta JC, et al. N Engl J Med. 2021 Sep 9;385(11):971-981. doi: 10.1056/NEJMoa2103879. Question and Methods: This study investigated... Read more.
Angiography after Out-of-Hospital Cardiac Arrest without ST-Segment Elevation
Methodology: 4/5 Usefulness: 4/5 Desch S, et al. N Engl J Med. 2021 Aug 29. doi: 10.1056/NEJMoa2101909. Question and Methods: This multi-center, open label RCT... Read more.
Effect of C-Reactive Protein-Guided Antibiotic Treatment Duration, 7-Day Treatment, or 14-Day Treatment on 30-Day Clinical Failure Rate in Patients with Uncomplicated Gram-Negative Bacteremia: A Randomized Clinical Trial
Methodology: 1/5 Usefulness: 1/5 von Dach E, et al. JAMA. 2020 Jun 2;323(21):2160-2169. doi: 10.1001/jama.2020.6348. Question and Methods: In a multi-center,... Read more.